Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3057 |
UNC1999
|
Histone Methyltransferase; Autophagy | Autophagy; Chromatin/Epigenetic |
UNC1999 是一种可口服的,选择性和 SAM-竞争性的 EZH2和 EZH1抑制剂,IC50分别为 <10 nM 和 45 nM。 | |||
T40038 |
UNC2399
UNC2399 |
||
UNC2399, a biotinylated version of UNC1999, functions as a selective degrader of EZH2 and exhibits strong in vitro efficacy against EZH2, demonstrated by its IC 50 value of 17 nM. |