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Targets Recommended: Sodium Channel

1

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T9461 AZ194

Sodium Channel Membrane transporter/Ion channel
CRMP2-Ubc9-NaV1.7 inhibitor 194 是一流的CRMP2-Ubc9相互作用抑制剂及NaV1.7抑制剂 (IC50=1.2 μM),口服有活性,具有抗伤害作用。AZ194 阻断 CRMP2 的 SUMOylation 以选择性地减少表面表达 NaV1.7 的量。

化合物

AZ194
Cat.No: T9461
Synonym:
Target: Sodium Channel
Cat. No. Product Name Species Expression System
TMPY-02608 UBC9/UBE2I Protein, Human, Recombinant

UBC9,ubiquitin-conjugating enzyme E2I,C358...

Human E. coli
UBE2I is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation, ubiquitination is believed nowadays to be crucial for a wider range of cellular processes. The outcome of the ubiquitin-conjugation reaction, and thereby the fate of the substrate, is heavily dependent on the number of ubiquitin molecules attached and how these ubiquitin molecules are inter-connected. To d...
TMPJ-01053 UBE2I Protein, Human, Recombinant (GST)

SUMO-Protein Ligase,Ubiquitin-Conjugating Enzyme E2 I,p18,

Human E. coli
SUMO-Conjugating Enzyme UBC9 (UBC9) belongs to the ubiquitin-conjugating enzyme family. UBC9 is homologous to ubiquitin-conjugating enzymes (E2s). However, instead of conjugating ubiquitin, UBC9 conjugates a ubiquitin homologue, Small Ubiquitin-Like Modifier 1 (SUMO-1). The conjugation of ubiquitin requires the activities of ubiquitin-activating (E1) and conjugating (E2) enzymes. It is suggested that UBC9 might play a role in DNA repair and perhaps even in aging.

重组蛋白

UBC9/UBE2I Protein, Human, Recombinant
Cat.No: TMPY-02608
Species: Human
Expression System: E. coli
UBE2I Protein, Human, Recombinant (GST)
Cat.No: TMPJ-01053
Species: Human
Expression System: E. coli
TargetMol Loading
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