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Search Results for " txn "

Targets Recommended: Others

2

抑制剂 & 化合物

18

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T13230	TXNIP-IN-1	Others	Others
	TXNIP-IN-1 是硫氧还蛋白-硫氧还蛋白相互作用蛋白复合物抑制剂。它在 TXNIP-TRX 复合物相关代谢紊乱的糖尿病、心血管疾病或炎症疾病方面有研究的价值。
T12817	(S)-TXNIP-IN-1	Others	Others
	(S)-TXNIP-IN-1 is the S-enantiomer of TXNIP-IN-1.

化合物

Cat.No: T13230

Target: Others

(S)-TXNIP-IN-1

Cat.No: T12817

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00382	Thioredoxin/TRX Protein, Mouse, Recombinant Txn,Txn1,thioredoxin	Mouse	E. coli
	Thioredoxin/TRX Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.7 kDa and the accession number is P10639.
TMPJ-00826	TXN Protein, Human, Recombinant (His) ADF,TXN,TRX1,Thioredoxin,TRX,ATL-Derived Factor,TRD...	Human	E. coli
	Thioredoxin (TXN) is a member of the Thioredoxin family. Thioredoxin exists as a disulfide-linked homodimer and contains one Thioredoxin domain. Thioredoxin is up-regulated by ionizing radiation. Thioredoxin participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Thioredoxin also plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contri...
TMPY-02250	Thioredoxin/TRX Protein, Human, Recombinant thioredoxin,TRDX,DKFZp686B1993,MGC61975,TXN,TRX1,RP...	Human	E. coli
	Thioredoxin/TRX Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.7 kDa and the accession number is P10599.
TMPY-02572	TXNDC17 Protein, Human, Recombinant thioredoxin domain containing 17,TXNL5,TRP14	Human	E. coli
	Thioredoxin-related protein of 14 kDa (TRP14, also called TXNDC17 for thioredoxin domain containing 17, or TXNL5 for thioredoxin-like 5) is an evolutionarily well-conserved member of the thioredoxin (Trx)-fold protein family that lacks activity with classical Trx1 substrates. TXNDC17 is a novel 14-kDa disulfide reductase of the TXN (thioredoxin) family. TXNDC17 is involved in the TNF (tumor necrosis factor) signaling pathway. Moreover, TXNDC17 plays an important role in Taxol resistance via enha...
TMPH-02929	TXNIP Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	TXNIP Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 46.4 kDa and the accession number is Q8BG60.
TMPH-02195	TXNDC17 Protein, Human, Recombinant (GST)	Human	E. coli
	Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.
TMPH-02196	TXNDC5 Protein, Human, Recombinant (GST)	Human	E. coli
	Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 63.2 kDa and the accession number is Q8NBS9.
TMPH-02198	TXNRD2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling.
TMPY-02797	TXNL4A Protein, Human, Recombinant (His) U5-15kD,thioredoxin-like 4A,DIB1,SNRNP15,TXNL4,BMKS...	Human	E. coli
	DIM1, also known as TXNL4A, is a member of the Dim protein family. The Dim protein family is composed of two classes, DIM1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their role in cell cycle progression and have been found to interact with Prp6, an essential component of the spliceosome, which forms the bridge of U4/U6.U5-tri-snRNP. Despite their biological and structural similarities, DIM1 and Dim2 proteins differ in many aspects. DIM1 bears distinc...
TMPY-06696	TXNDC15 Protein, Human, Recombinant (His) UNQ335,thioredoxin domain containing 15,C5orf14,UNQ335/PRO53...	Human	HEK293 Cells
	TXNDC15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.96 kDa and the accession number is NP_078991.3.
TMPJ-00720	TXNDC12 Protein, Human, Recombinant (His) TLP19,ERp19,Thioredoxin Domain-Containing Protein 12,hTLP19,...	Human	HEK293 Cells
	Thioredoxin Domain-Containing Protein 12 belongs to the thioredoxin superfamily. In this family, proteins possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors. TXNDC12 is widely expressed in many tissues and contains one thioredoxin domain.
TMPH-02200	TXNIP Protein, Human, Recombinant (B2M & His)	Human	E. coli
	TXNIP Protein, Human, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 57.7 kDa and the accession number is Q9H3M7.
TMPH-02197	TXNDC5 Protein, Human, Recombinant	Human	E. coli
	Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 36.2 kDa and the accession number is Q8NBS9.
TMPH-02199	TXNRD2 Protein, Human, Recombinant (His)	Human	E. coli
	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. TXNRD2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.5 kDa and the accession number is P30048.
TMPY-02723	TXNL4B Protein, Human, Recombinant (His) DLP,Dim2,thioredoxin-like 4B	Human	E. coli
	Dim2, also known as TXNL4B, is a member of the DIM1 family. The Dim protein family is composed of two classes, Dim1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their role in cell cycle progression and have been found to interact with Prp6, an essential component of the spliceosome, which forms the bridge of U4/U6.U5-tri-snRNP. Despite their biological and structural similarities, Dim1 and Dim2 proteins differ in many aspects. Dim1 bears distinctive st...
TMPY-02271	TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His) thioredoxin reductase 1,TR1,TXNR,TR,TRXR1,GRIM-12	Human	E. coli
	Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor th...
TMPH-02587	CIRBP Protein, Mouse, Recombinant (His) CIRP,A18 hnRNP,Glycine-rich RNA-binding protein CIRP,CIRBP,C...	Mouse	E. coli
	Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Promotes assembly of stress granules (SGs), when overexpressed. Seems to play an essential role in cold-induced suppression of cell proliferation. Acts as a translational repressor. Acts as a translational activator. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN.
TMPY-02084	Thioredoxin 2/TRX2 Protein, Human, Recombinant (His) MT-TRX,RP5-1119A7. 13-005,TRX2,MTRX,thioredoxin 2	Human	E. coli
	Thioredoxin-2, also known as TXN2, MTRX and TRX2, is a member of the thioredoxin family. Tryparedoxins (TXN) are thioredoxin-related proteins which, as trypanothione:peroxiredoxin oxidoreductases, constitute the trypanothione-dependent antioxidant defense and may also serve as substrates for ribonucleotide reductase in trypanosomatids. Thioredoxin-2 / TXN2 contains one thioredoxin domain. It is widely expressed in adult (at protein level) and fetal tissues. Human Thioredoxin-2 / TXN2 is a small ...

重组蛋白

Thioredoxin/TRX Protein, Mouse, Recombinant

Cat.No: TMPY-00382

Species: Mouse

Expression System: E. coli

TXN Protein, Human, Recombinant (His)

Cat.No: TMPJ-00826

Species: Human

Expression System: E. coli

Thioredoxin/TRX Protein, Human, Recombinant

Cat.No: TMPY-02250

Species: Human

Expression System: E. coli

TXNDC17 Protein, Human, Recombinant

Cat.No: TMPY-02572

Species: Human

Expression System: E. coli

TXNIP Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02929

Species: Mouse

Expression System: P. pastoris (Yeast)

TXNDC17 Protein, Human, Recombinant (GST)

Cat.No: TMPH-02195

Species: Human

Expression System: E. coli

TXNDC5 Protein, Human, Recombinant (GST)

Cat.No: TMPH-02196

Species: Human

Expression System: E. coli

TXNRD2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02198

Species: Human

Expression System: E. coli

TXNL4A Protein, Human, Recombinant (His)

Cat.No: TMPY-02797

Species: Human

Expression System: E. coli

TXNDC15 Protein, Human, Recombinant (His)

Cat.No: TMPY-06696

Species: Human

Expression System: HEK293 Cells

TXNDC12 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00720

Species: Human

Expression System: HEK293 Cells

TXNIP Protein, Human, Recombinant (B2M & His)

Cat.No: TMPH-02200

Species: Human

Expression System: E. coli

TXNDC5 Protein, Human, Recombinant

Cat.No: TMPH-02197

Species: Human

Expression System: E. coli

TXNRD2 Protein, Human, Recombinant (His)

Cat.No: TMPH-02199

Species: Human

Expression System: E. coli

TXNL4B Protein, Human, Recombinant (His)

Cat.No: TMPY-02723

Species: Human

Expression System: E. coli

TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)

Cat.No: TMPY-02271

Species: Human

Expression System: E. coli

CIRBP Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02587

Species: Mouse

Expression System: E. coli

Thioredoxin 2/TRX2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02084

Species: Human

Expression System: E. coli

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