Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T61472 |
Tubulin inhibitor 18
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Tubulin inhibitor 18 (compound 5j) is a highly potent chalcone compound that effectively inhibits tubulin. Its unique molecular structure renders Tubulin inhibitor 18 as a promising candidate for cancer research [1]. | |||
T17181 |
TVB-3664
|
Fatty Acid Synthase | Metabolism |
TVB-3664 是一种具有口服具有活力的、选择性的、可逆的、具有高生物利用度的脂肪酸合酶抑制剂,其对人和老鼠棕榈酸酯合成的IC50分别为 18 nM 和 12 nM。可显著抑制微管蛋白棕榈酰化和 mRNA 表达。 | |||
T62477 |
Tubulin polymerization-IN-18
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Tubulin aggregation-IN-18 (compound 3) 是一种有效的 tubulin 聚合抑制剂,具有潜力进行乳腺癌和耐药结肠癌的研究。 | |||
T36856 |
UA 62784
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Inhibitor of microtubule polymerization in vitro. Interacts with tubulin dimers and promotes the accumulation of mammalian cells in apoptosis. Potentiates antiproliferative effects of vinblastine in H2B-GFP HeLa cells. Originally thought to inhibit CENP-E ATPase activity. Tcherniuk et al (2011) UA62784 is a cytotoxic inhibitor of microtubules, not CENP-E. Chem.Biol. 18 631 PMID:21609844 |Maiato and Logarinho et al (2011) Motor-dependent and -independent roles of CENP-E at kinetochores: the cauti... |