Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T67935 |
Tubulin inhibitor 11
|
Apoptosis; Microtubule Associated | Apoptosis; Cytoskeletal Signaling |
Tubulin inhibitor 11 是一种口服活性的有效微管蛋白抑制剂。它通过靶向秋水仙碱结合位点,抑制tubulin聚合,进而促进有丝分裂阻断和apoptosis。 | |||
T13225 | Tubulin inhibitor 7 | Microtubule Associated | Cytoskeletal Signaling |
Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (IC50: 11 nM)). | |||
T62498 |
Tubulin polymerization-IN-20
|
||
Tubulin aggregation-IN-20 (compound 11) 是一种有效的 tubulin 聚合抑制剂。Tubulin aggregation-IN-20 具有潜力进行乳腺癌和耐药结肠癌的研究。 | |||
T10640 |
C-11
|
Others | Others |
C-11 is a tubulin inhibitor and acts as an ADC cytotoxin with cytotoxicity for carcinoma cell lines. | |||
T79206 |
MC-EVCit-PAB-MMAE
|
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MC-EVCit-PAB-MMAE (Linker-Payload 11) 作为一种ADC (drug-linker conjugates) 的代表,由具有功能性的ADC linker (MC-EVCit-PAB) 以及作为有效药物负载的微管蛋白聚合抑制剂MMAE组成。 |