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Cat. No. Product Name Target Signaling Pathways
T21224 (+)-Fluprostenol

Fluprostenol, (+)-,Travoprost acid,AL-5848,曲伏前列素酸

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
(+)-Fluprostenol (AL-5848) 是前列腺素 F2 α 的类似物,是一种前列腺素 F2α 受体 PTGFR 激动剂,可降低输卵管糖蛋白 1 (OVGP1) 的表达。
T37946 17-trifluoromethylphenyl trinor Prostaglandin F2α

17-trifluoromethylphenyl trinor Prostaglandin F2α

A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists. 17-trifluoromethylphenyl trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trin...
T37947 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester

17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester

Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor PGF2α is an analog of PGF2α that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2α methyl ester is a lipophil...
T37948 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α

17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α

A number of 17-phenyl trinor prostaglandin F2α(17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.1,2,3Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency, but show a significantly reduced incidence of local irritant side effects.417-trifluoromethylphenyl-13,14-dihydro trinor PGF2αbears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As a...
T37777 17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide

17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide

Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor Prostaglandin F2α (17-trifluoromethylphenyl trinor PGF2α) is an analog of PGF2α that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoro...

化合物

(+)-Fluprostenol
Cat.No: T21224
Synonym: Fluprostenol, (+)-,Travoprost acid,AL-5848,曲伏前列素酸
Target: Prostaglandin Receptor
17-trifluoromethylphenyl trinor Prostaglandin F2α
Cat.No: T37946
Synonym: 17-trifluoromethylphenyl trinor Prostaglandin F2α
Target:
17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester
Cat.No: T37947
Synonym: 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester
Target:
17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α
Cat.No: T37948
Synonym: 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α
Target:
17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide
Cat.No: T37777
Synonym: 17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide
Target:
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