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Cat. No. Product Name Target Signaling Pathways
T79914 Tranylcypromine

SKF 385

Monoamine Oxidase Neuroscience
Tranylcypromine (SKF 385)为一种高效的单胺氧化酶抑制剂。
T7942 Tranylcypromine hemisulfate

Tranylcypromine Sulfate,Tranylcypromine (hemisulfate),反苯环丙胺半硫酸盐

Histone Demethylase; MAO; Monoamine Oxidase Chromatin/Epigenetic; Metabolism; Neuroscience
Tranylcypromine hemisulfate (Tranylcypromine Sulfate) 是单胺氧化酶(MAO) 和赖氨酸特异性去甲基化酶 1 (LSD1) 的抑制剂,可用于研究抑郁症和子宫内膜异位症。
T1025 Tranylcypromine (2-PCPA) hydrochloride

反苯环丙胺盐酸盐,Tranylcypromine (2-PCPA) HCl,SKF-385 HCl

Histone Demethylase; MAO Chromatin/Epigenetic; Metabolism; Neuroscience
Tranylcypromine (2-PCPA) hydrochloride (SKF-385 HCl) 是一种单胺氧化酶抑制剂,对治疗重度抑郁症、心境恶劣障碍和非典型抑郁症有效。
T71826 (1S,2R)-Tranylcypromine hydrochloride

(1S,2R)-SKF 385 hydrochloride

(1S,2R)-Tranylcypromine ((1S,2R)-SKF 385) hydrochloride 是一种有效的抗抑郁 (antidepressant) 剂。(1S,2R)-Tranylcypromine hydrochloride 对 MAO 和 LSD1有抑制作用。
T12701 (rel)-Tranylcypromine D5 hydrochloride

2-Phenylcyclopropylamine D5 hydrochloride

Histone Demethylase Chromatin/Epigenetic
(rel)-Tranylcypromine D5 hydrochloride is a deuterium labeled (rel)-Tranylcypromine hydrochloride. (rel)-Tranylcypromine hydrochloride is an irreversible, nonselective inhibitor of monoamine oxidase (MAO) used in the treatment of depression.
T39799 S2157

S2157

S2157, a potent N-alkylated tranylcypromine (TCP) derivative lysine-specific demethylase 1 (LSD1) inhibitor, enhances H3K9 methylation and concurrently reduces H3K27 acetylation at super-enhancer sites. This compound triggers apoptosis in TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells by inhibiting NOTCH3 and TAL1 gene expression. Moreover, S2157 is capable of crossing the blood-brain barrier, effectively eliminating central nervous system (CNS) leukemia in mice models implanted...
T39800 S2116

S2116 is a powerful inhibitor of lysine-specific demethylase 1 (LSD1), and it is a derivative of N-alkylated tranylcypromine (TCP). S2116 exhibits its inhibitory effects by increasing H3K9 methylation and inducing reciprocal H3K27 deacetylation at super-enhancer regions. In TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells, S2116 triggers apoptosis by repressing the transcription of NOTCH3 and TAL1 genes. Furthermore, S2116 demonstrates significant growth retardation of T-ALL cells...

化合物

Tranylcypromine
Cat.No: T79914
Synonym: SKF 385
Target: Monoamine Oxidase
Tranylcypromine hemisulfate
Cat.No: T7942
Synonym: Tranylcypromine Sulfate,Tranylcypromine (hemisulfate),反苯环丙胺半硫酸盐
Target: Histone Demethylase, MAO, Monoamine Oxidase
Tranylcypromine (2-PCPA) hydrochloride
Cat.No: T1025
Synonym: 反苯环丙胺盐酸盐,Tranylcypromine (2-PCPA) HCl,SKF-385 HCl
Target: Histone Demethylase, MAO
(1S,2R)-Tranylcypromine hydrochloride
Cat.No: T71826
Synonym: (1S,2R)-SKF 385 hydrochloride
Target:
(rel)-Tranylcypromine D5 hydrochloride
Cat.No: T12701
Synonym: 2-Phenylcyclopropylamine D5 hydrochloride
Target: Histone Demethylase
S2157
Cat.No: T39799
Synonym: S2157
Target:
S2116
Cat.No: T39800
Synonym:
Target:
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