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1

抑制剂 & 化合物

8

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T78107	Reltecimod TFA AB-103 TFA
	Reltecimod (AB-103) TFA 是一款针对 T 细胞特异性表面糖蛋白CD28(TP44) 的拮抗剂。该化合物能够有效抵御各类细菌感染、细菌产生的外毒素和内毒素，以及电离辐射。其通过特异性目标定位并调节 CD28/B7-2 共刺激通路以减弱炎症反应，但并不完全抑制该通路。Reltecimod TFA 主要用于坏死性软组织感染(NSTIs)的研究。

化合物

Cat.No: T78107

Synonym: AB-103 TFA

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01941	CD28 Protein, Human, Recombinant (hFc) Tp44,CD28 molecule	Human	HEK293
	CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell r...
TMPY-05354	CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated CD28 molecule,Tp44	Human	HEK293
	CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell r...
TMPJ-00103	CD28 Protein, Human/Cynomolgus, Recombinant (His) CD28 antigen,CD28 molecule,T-cell-specific surface glycoprot...	Human,Cynomolgus	Human Cells
	T-cell-specific surface glycoprotein CD28(CD28) is a single-pass typeI membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. It belongs to the immunoglobulin(Ig) superfamily. CD28 is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation.CD28 co-stimulation is necessary for CD4 positive T-cell proliferation and survival, interleukin-2 production, and T-helper type-2 development. Human post-thymic regulat...
TMPK-01177	CD28 Protein, Canine, Recombinant (mFc) CD28 molecule,CD28 antigen (Tp44),CD28,MGC...	Canine	HEK293
	CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
TMPK-00110	CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi) CD28 molecule,MGC138290,CD28,CD28 antigen (Tp44...	Human,Cynomolgus,Rhesus macaque	HEK293
	CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
TMPK-00111	CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi), Biotinylated CD28 antigen (Tp44),CD28 molecule,CD28,MGC...	Human,Cynomolgus,Rhesus macaque	HEK293
	CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
TMPK-01176	CD28 Protein, Canine, Recombinant (His) CD28 antigen (Tp44),MGC138290,CD28,CD28 mo...	Canine	HEK293
	CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
TMPJ-00102	CD28 Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated CD28 molecule,CD28 antigen,CD28,TP44,T-cel...	Human,Cynomolyus	Human Cells
	T-cell-specific surface glycoprotein CD28(CD28) is a single-pass typeI membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. It belongs to the immunoglobulin(Ig) superfamily. CD28 is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation.CD28 co-stimulation is necessary for CD4 positive T-cell proliferation and survival, interleukin-2 production, and T-helper type-2 development. Human post-thymic regulat...

重组蛋白

CD28 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01941

Species: Human

Expression System: HEK293

CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-05354

Species: Human

Expression System: HEK293

CD28 Protein, Human/Cynomolgus, Recombinant (His)

Cat.No: TMPJ-00103

Species: Human,Cynomolgus

Expression System: Human Cells

CD28 Protein, Canine, Recombinant (mFc)

Cat.No: TMPK-01177

Species: Canine

Expression System: HEK293

CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi)

Cat.No: TMPK-00110

Species: Human,Cynomolgus,Rhesus macaque

Expression System: HEK293

CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00111

Species: Human,Cynomolgus,Rhesus macaque

Expression System: HEK293

CD28 Protein, Canine, Recombinant (His)

Cat.No: TMPK-01176

Species: Canine

Expression System: HEK293

CD28 Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPJ-00102

Species: Human,Cynomolyus

Expression System: Human Cells

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