Cat. No. | Product Name | Target | Signaling Pathways |
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T17073 |
Thioflavin T
Basic Yellow 1,硫黄素 T,硫黄素T |
Others | Others |
Thioflavin T (Basic Yellow 1) 是阳离子 Benzothiazole 染料,在组织切片中能够淀粉样蛋白结合,增强荧光强度。 | |||
T60335 |
BTA-1
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BTA-1 是一种不带电的硫代黄素-T 衍生物。BTA-1 对 Aβ 原纤维具有高亲和力,并具有良好的脑进入和清除能力。 | |||
T78173 |
Aβ/tau aggregation-IN-3
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Aβ/tau aggregation-IN-3为一种高效的抗Aβ聚集剂,经Aβ-硫黄素T (Aβ-ThT) 聚集测定显示,其半抑制浓度(IC50)为0.85 μM,表现出显著的抗淀粉样蛋白活性。 | |||
T37370 |
Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)
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Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red and are organized in a cross-β arrangement of β-strands similar to Aβ (1-40) and Aβ (1-42) fibrils. Aggregated Aβ (25-35) decreases the viability of rat adrenal PC12 cells. It also decreases the viability of primary rat cortical neurons at concentrations ranging from 1 nM to 30 μM.... | |||
T35627 |
Amylin (human) (trifluoroacetate salt)
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Amylin is a 37-residue peptide hormone secreted from pancreatic β-cells that reduces food intake, decreases glucagon secretion, slows gastric emptying, and increases satiety. It binds to amylin receptors with IC50 values of 2 and 0.2 nM for porcine and guinea pig nucleus accumbens membrane preparations, respectively. Amylin is present in amyloid aggregates derived from the pancreatic islets of humans with type 2 diabetes. Amylin forms fibrils that react to thioflavin T and are organized in a cro... |