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Search Results for " tr1 "

Targets Recommended: Others

6

抑制剂 & 化合物

13

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T9334	TbPTR1 inhibitor 2	Others	Others
	TbPTR1 inhibitor 2 被确定为改进的蝶啶还原酶-1 (PTR1) 抑制剂和抗锥虫药物的新发展。
T61912	TbPTR1 inhibitor 1
	TbPTR1 inhibitor 1 (compound 5d) 是有效的动基体蝶啶还原酶 1 (PTR1)抑制剂。TbPTR1 inhibitor 1抑制布氏锥虫 PTR1 (TbPTR1) 的 IC50<0.1 nM，抑制布氏锥虫 (Trypanosoma brucei) 活性的 EC50=0.66 μM。
T37300	PCTR1 PCTR1
	Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is then converted to PCTR1 by glutathione S-transferase. PCTR1 levels increase during resolution of acute microbial-induced peritonitis in mice. PCTR1 (30 ng, i.p.) administration 12 hours post-infection increases macrophage numbers and activity and shortens the resolution phase of inflammation by 57%. It als...
T37505	MCTR1 MCTR1
	Maresin conjugates in tissue regeneration 1 (MCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is then converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase. MCTR1 accelerates tissue regeneration in planaria (1 and 100 nM). Pretreatment with MCTR1 (50 ng/mouse, i.p.) prior to E. coli administration reduces neutrophil infiltration, shortens the inflam...
T37529	TC NTR1 17
	Non-peptide neurotensin receptor 1 (NTS1) partial agonist (EC50 <15.6 nM and Emax = 63% of neurotensin response in Ca2+ mobilization assay). Exhibits over 50-fold selectivity for NTS1 over NTS2 and GPR35. Hershberger et al (2014) Imidazole-derived agonists for the neurotensin 1 receptor. Bioorg.Med.Chem.Lett. 24 262 PMID:24332089
T37166	RCTR1
	Resolvin conjugate in tissue regeneration 1 (RCTR1) is a specialized pro-resolving mediator (SPM) biosynthesized from docosahexaenoic acid by isolated human macrophages and apoptotic polymorphonuclear (PMN) neutrophils.1It has been found in human spleen and bone marrow.2RCTR1 is produced via lipoxygenase-mediated oxidation of DHA to 7(S)-8-epoxy-17(S)-HDHA, which is conjugated to glutathione.1,2,3RCTR1 (10 nM) increases phagocytosis ofE. colior apoptotic neutrophils in isolated human monocyte-de...

化合物

TbPTR1 inhibitor 2

Cat.No: T9334

Target: Others

TbPTR1 inhibitor 1

Cat.No: T61912

Cat.No: T37300

Synonym: PCTR1

Cat.No: T37505

Synonym: MCTR1

Cat.No: T37529

Cat.No: T37166

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04509	Osteoprotegerin Protein, Mouse, Recombinant (hFc) tumor necrosis factor receptor superfamily member 1...	Mouse	HEK293 Cells
	Osteoprotegerin Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.2 kDa and the accession number is O08712.
TMPY-02271	TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His) thioredoxin reductase 1,TR1,TXNR,...	Human	E. coli
	Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor th...
TMPY-04202	Tomoregulin-1 Protein, Mouse, Recombinant (hFc) M7365,transmembrane protein with EGF-like and two f...	Mouse	HEK293 Cells
	TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEFF1 may behave as a tumor suppressor gene in brain cancers. TMEFF1 and TMEFF2 are putative transmembrane proteins comprised of one epidermal growth factor (EGF)-like domain and two follistatin-like domains. Both TMEFF1 and TMEFF2 are predominantly expressed in the brain. Tomoregul...
TMPY-05262	Osteoprotegerin Protein, Human, Recombinant (hFc) MGC29565,OPG,PDB5,tumor necrosis factor receptor superfamily...	Human	Baculovirus Insect Cells
	Osteoprotegerin Protein, Human, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 70.3 kDa and the accession number is O00300.
TMPY-01724	Osteoprotegerin Protein, Human, Recombinant (His) OCIF,OPG,MGC29565,TR1,PDB5,tumor necrosis ...	Human	HEK293 Cells
	Osteoprotegerin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.3 kDa and the accession number is O00300.
TMPY-00112	Tomoregulin-1 Protein, Human, Recombinant (hFc) TR-1,C9orf2,transmembrane protein...	Human	HEK293 Cells
	TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEFF1 may behave as a tumor suppressor gene in brain cancers. TMEFF1 and TMEFF2 are putative transmembrane proteins comprised of one epidermal growth factor (EGF)-like domain and two follistatin-like domains. Both TMEFF1 and TMEFF2 are predominantly expressed in the brain. Tomoregul...
TMPH-00861	HTR1D Protein, Human, Recombinant (His & KSI)	Human	E. coli
	HTR1D Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 19.5 kDa and the accession number is P28221.
TMPH-00860	HTR1D Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	HTR1D Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 33.1 kDa and the accession number is P28221.
TMPH-03402	STR1 Protein, Rauvolfia serpentina, Recombinant (His & Myc)	Rauvolfia serpentina	E. coli
	Catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine, the key intermediate of indole alkaloid biosynthesis. STR1 Protein, Rauvolfia serpentina, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.2 kDa and the accession number is P68175.
TMPH-00862	HTR1F Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. HTR1F Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO ...
TMPH-00859	HTR1B Protein, Human, Recombinant (His)	Human	E. coli
	HTR1B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 45.1 kDa and the accession number is P28222.
TMPH-03749	CYSLTR1 Protein, Human, Recombinant (His) Cysteinyl leukotriene receptor 1,G-protein...	Human	E. coli
	Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
TMPY-00374	SSTR1 Protein, Human, Recombinant (hFc) TRAPA,signal sequence receptor, α,signal sequence r...	Human	HEK293 Cells
	SSTR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.8 kDa and the accession number is P43307-1.

重组蛋白

Osteoprotegerin Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-04509

Species: Mouse

Expression System: HEK293 Cells

TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)

Cat.No: TMPY-02271

Species: Human

Expression System: E. coli

Tomoregulin-1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-04202

Species: Mouse

Expression System: HEK293 Cells

Osteoprotegerin Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05262

Species: Human

Expression System: Baculovirus Insect Cells

Osteoprotegerin Protein, Human, Recombinant (His)

Cat.No: TMPY-01724

Species: Human

Expression System: HEK293 Cells

Tomoregulin-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00112

Species: Human

Expression System: HEK293 Cells

HTR1D Protein, Human, Recombinant (His & KSI)

Cat.No: TMPH-00861

Species: Human

Expression System: E. coli

HTR1D Protein, Human, Recombinant (hFc)

Cat.No: TMPH-00860

Species: Human

Expression System: HEK293 Cells

STR1 Protein, Rauvolfia serpentina, Recombinant (His & Myc)

Cat.No: TMPH-03402

Species: Rauvolfia serpentina

Expression System: E. coli

HTR1F Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-00862

Species: Human

Expression System: E. coli

HTR1B Protein, Human, Recombinant (His)

Cat.No: TMPH-00859

Species: Human

Expression System: E. coli

CYSLTR1 Protein, Human, Recombinant (His)

Cat.No: TMPH-03749

Species: Human

Expression System: E. coli

SSTR1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00374

Species: Human

Expression System: HEK293 Cells

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