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Cat. No.	Product Name	Target	Signaling Pathways
T3049	TPCA-1 GW683965,IKK2 Inhibitor IV,TPCA1	Apoptosis; IκB/IKK; STAT	Apoptosis; JAK/STAT signaling; NF-κB; Stem Cells
	TPCA-1 (TPCA1) 是一种选择性IKK-2抑制剂，IC50值为 17.9 nM。它也是反式激活、DNA 结合以及STAT3磷酸化的一种抑制剂。
T38158	StA-IFN-1
	StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1 , which specifically inhibits the IKKβ component of the IFN induction pathway. It does not show inhibitory activity in a GFP reporter assay for IFN signaling in which ruxolitinib , which is specific for the IFN signaling component JAK1, is active. StA-IFN-1 reduces the levels of IFN-β, but not ISG MxA, mRNA, suggesting that it is selective f...