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Search Results for " tnni3 "

Targets Recommended: Others

2

抑制剂 & 化合物

5

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T24109	GSK329 GSK 329,GSK-329	Others	Others
	GSK329 是一种有效的选择性 TNNI3 相互作用激酶 (TNNI3K) 抑制剂。 GSK329 在缺血/再灌注心脏损伤模型中表现出积极的心脏保护作用。
T22341	GSK-114	Others	Others
	GSK 114 是口服有活性的、高选择性的TNNI3K 抑制剂 (IC50= 25 nM)。其中TNNI3K (又称 CARK) 是酪氨酸样激酶家族的成员，选择性在心脏组织中表达。它对 TNNI3K 的选择性是 B-Raf 激酶的 40 倍 (IC50= 1 µM)。

化合物

Cat.No: T24109

Synonym: GSK 329,GSK-329

Target: Others

Cat.No: T22341

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00044	TNNC1 Protein, Human, Recombinant (His) TNNC1,Troponin I,CMH7,TNNI3	Human	E. coli
	Troponin I, also known as TNI, is a 24 kDa component of a protein complex on striated muscle thin filaments.Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. Troponin I inhibits the calcium-dependent muscle contraction mediated by Troponins...
TMPH-02954	TNNI3 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. TNNI3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 40.1 kDa and the accession number is P48787.
TMPH-02634	TRIM63 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striate...
TMPH-03282	TRIM63 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striate...
TMPH-01271	TRIM63 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striate...

重组蛋白

TNNC1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00044

Species: Human

Expression System: E. coli

TNNI3 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02954

Species: Mouse

Expression System: E. coli

TRIM63 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02634

Species: Mouse

Expression System: E. coli

TRIM63 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03282

Species: Rat

Expression System: E. coli

TRIM63 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01271

Species: Human

Expression System: E. coli

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