Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-01064 |
GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc)
GITRL,GITR Ligand,TL6,TNFSF18,AITRL |
Mouse | HEK293 Cells |
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept. GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is ... | |||
TMPK-00053 |
GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag)
AITRL,TNFSF18,TL6,GITR Ligand,GITRL |
Human | HEK293 Cells |
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept. GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecula... | |||
TMPK-00054 |
GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
TL6,GITR Ligand,TNFSF18,AITRL,GITRL |
Human | HEK293 Cells |
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept. GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated is expressed in HEK293 mammalian cells with... | |||
TMPJ-00432 |
GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)
GITRL,TNFSF18,Activation-inducible TNF-rel... |
Cynomolgus | HEK293 Cells |
TNFSF18 is a single-pass type II membrane protein. It is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 cytokine binds to TNFRSF18/AITR/GITR. It regulates T-cell responses, and functions as costimulator and lower the threshold for T-cell activation and T-cell proliferation. It is Important for interactions between activated T-lymphocytes and endothelial cells and Promotes leukocyte adhesion to endothelial cells. TNFSF18 mediates activation ... | |||
TMPK-01260 |
GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (aa 20-156, His)
TNFRSF18,GITR-D,AITR,CD357,GITR |
Cynomolgus | HEK293 Cells |
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (aa 20-156, His) is expressed in HEK293 ... | |||
TMPK-00132 |
GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His & Avi), Biotinylated
GITR-D,CD357,AITR,GITR,TNFRSF18 |
Human | HEK293 Cells |
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His & Avi), Biotinylated is expre... | |||
TMPK-00133 |
GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His)
GITR-D,AITR,GITR,CD357,TNFRSF18 |
Human | HEK293 Cells |
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His) is expressed in HEK293 mamma... | |||
TMPK-01086 |
GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His)
TNFRSF18,AITR,GITR-D,CD357,GITR |
Mouse | HEK293 Cells |
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His) is expressed in HEK293 mamma... | |||
TMPJ-00110 |
GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His)
Tnfrsf18,GITR-D,CD357,AITR,Tumor necrosis factor re... |
Mouse | HEK293 Cells |
Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1, TRAF2, and... |