Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9590 |
T-1095
|
SGLT; transporter | GPCR/G Protein; Metabolism |
T-1095 是一种口服有活性的Na+-葡萄糖协同转运蛋白选择性抑制剂,能够抑制 SGLT1 (IC50:22.8 µm) 及 SGLT2 (IC50:2.3 µm) 。它可用于研究糖尿病。 | |||
T28897 |
T-1095A
T 1095A,J1.265.331J |
||
T-1095A is an active metabolite of T-1095, a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs). Chronic administration of T-1095 (0.1% w w(-1) pellet chow, for 12 weeks) decreased blood glucose and haemoglobin A(1C) levels, and improved |