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Cat. No.	Product Name	Target	Signaling Pathways
T35781	Sphinganine (d20:0) Sphinganine (d20:0)
	Sphinganine (d20:0) is a natural isomer of dihydro-D-erythro-sphinganine (sphinganine (d18:0); that is a precursor of ceramide and sphingosine as well as a substrate for sphingosine kinases, which generate sphingosine-1-phosphate (d18:1) . In S. cerevisiae, the amount of sphinganine (d20:0) increases 10.8-fold in response to heat stress, indicating it is involved in heat stress adaptation. Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins as well ...
T36437	Sphinganine (d17:0) Sphinganine (d17:0)
	Sphinganine is a synthetic bioactive sphingolipid that inhibits the growth of C. glabrata and C. albicans with a minimum fungicidal concentration (MFC) value of 0.5 μg/ml for both. More commonly, sphinganine is used as an internal standard in the analysis of sphingoid compounds by chromatographic or spectrometric methods.
T39401	Sphinganine 1-phosphate D-erythro-Dihydrosphingosine 1-phosphate,Sphinganine 1-phosphate
	Sphinganine 1-phosphate, also known as D-erythro-Dihydrosphingosine 1-phosphate, is a polar sphingolipid metabolite. It plays a crucial role in regulating various cellular processes including cell migration, differentiation, survival, and complex physiological processes.
T37952	Sphinganine-1-phosphate (d17:0) Sphinganine-1-phosphate (d17:0)
	Sphinganine-1-phosphate (d17:0) is a sphingolipid analog of sphinganine-1-phosphate (d18:0) and sphingosine-1-phosphate (d18:1) that has a 17-carbon base. Sphinganine-1-phosphate (d17:0) levels are lower in surgical and cadaver trabecular meshwork samples isolated from patients with primary open angle glaucoma compared with control samples.
T36987	N,N-dimethyl Sphinganine (d18:0) N,N-dimethyl Sphinganine (d18:0)
	N,N-dimethyl Sphinganine (d18:0) is a sphingolipid that increases during development ofL. donovanipromastigotes.1 1.Silva, A.M., Cordeiro-da-Silva, A., and Coombs, G.H.Metabolic variation during development in culture of Leishmania donovani promastigotesPLoS Negl. Trop. Dis.5(12)e1451(2011)
T37010	D-threo Sphinganine (d18:0) D-threo Sphinganine (d18:0)
	D-threo Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and L-erythro sphinganine (d18:0) . It induces autophagy in HCT116 cells when used at a concentration of 12 μM. D-threo Sphinganine (d18:0) is metabolized via sphinganine N-acyltransferase and sphinganine kinase in vivo in rat liver.
T36613	DL-erythro/threo Sphinganine (d16:0) DL-erythro/threo Sphinganine (d16:0)
	DL-erythro/threo Sphinganine (d16:0) is a sphingolipid that is decreased in rats following long-term, low-dose administration of dimethoate and is used as a biomarker for dimethoate exposure. It has been found in the fermentation broth of Bacterium SRCnm, which has antimicrobial and antioxidant activities. This product is a mixture of sphinganine (d16:0), L-erythro sphinganine (d16:0), D-threo sphinganine (d16:0), and L-threo sphinganine (d16:0).
T82794	C6-NBD Sphinganine
	C6-NBD Sphinganine, 一种荧光染料, 用于标记鞘氨酸类似物的脂肪酸。
T37454	C16 dihydro Ceramide (d18:0/16:0) Ceramide (d18:0/16:0),Cer(d18:0/16:0),N-hexadecanoyl-D-erythro-Dihydrosphingosine,N-Palmitoyl Sphinganine
	C16 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C16 ceramide (d18:0/16:0) that lacks the 4,5-trans double bond.[1] C16 dihydro Ceramide (0-46 nM) inhibits C16 ceramide-induced membrane permeabilization, measured as cytochrome C oxidation, in rat liver mitochondria in a concentration-dependent manner. It also inhibits C16 ceramide-induced channel formation in liposomes. C16 dihydro ceramide is biologically inactive as a single agent, lacking the ability ...
T36833	A6770
	A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.1It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50= <0.01 μM), an effect that is reduced in the presence of vitamin B6(EC50= <100 μM). 1.Ohtoyo, M., Tamura, M., Machinaga, N., et al.Scintillation proximity assay to detect the changes in cellular dihydrosphingosine 1-phosphate levelsLipids51(10)1207-1216(2016)

化合物

Sphinganine (d20:0)

Cat.No: T35781

Synonym: Sphinganine (d20:0)

Target:

Sphinganine (d17:0)

Cat.No: T36437

Synonym: Sphinganine (d17:0)

Target:

Sphinganine 1-phosphate

Cat.No: T39401

Synonym: D-erythro-Dihydrosphingosine 1-phosphate,Sphinganine 1-phosphate

Target:

Sphinganine-1-phosphate (d17:0)

Cat.No: T37952

Synonym: Sphinganine-1-phosphate (d17:0)

Target:

N,N-dimethyl Sphinganine (d18:0)

Cat.No: T36987

Synonym: N,N-dimethyl Sphinganine (d18:0)

Target:

D-threo Sphinganine (d18:0)

Cat.No: T37010

Synonym: D-threo Sphinganine (d18:0)

Target:

DL-erythro/threo Sphinganine (d16:0)

Cat.No: T36613

Synonym: DL-erythro/threo Sphinganine (d16:0)

C16 dihydro Ceramide (d18:0/16:0)

Cat.No: T37454

Synonym: Ceramide (d18:0/16:0),Cer(d18:0/16:0),N-hexadecanoyl-D-erythro-Dihydrosphingosine,N-Palmitoyl Sphinganine

Cat. No.	Product Name	Target	Signaling Pathways
T13632	D-Erythro-dihydrosphingosine Dihydrosphingosine,Octadecasphinganine,D-赤式-C 18 - 二氢-D-神经鞘氨醇,C18-Dihydrosphingosine,D-erythro-Sphinganine	Phospholipase; Endogenous Metabolite	Metabolism
	D-Erythro-dihydrosphingosine (C18-Dihydrosphingosine) 可抑制花生四烯酸的释放和cPLA2α活性。

天然产物

D-Erythro-dihydrosphingosine

Cat.No: T13632

Synonym: Dihydrosphingosine,Octadecasphinganine,D-赤式-C 18 - 二氢-D-神经鞘氨醇,C18-Dihydrosphingosine,D-erythro-Sphinganine

Target: Phospholipase, Endogenous Metabolite

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