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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T38055 Salvinorin A Propionate

Salvinorin A propionate is a selective partial agonist at κ1-opioid receptors (KOR) with a Ki value of 32.6 nM. It inhibits adenylate cyclase (EC50 = 4.7 nM) in HEK293 cells transfected with human KOR. It is selective for KORs over μ, δ, and ORL-1 opioid receptors and has no effect at serotonin, dopamine, muscarinic, or adrenergic receptors. In mice, salvinorin A propionate (13 μg, i.c.v.) reduces nociceptive responses in a radiant heat tail-flick assay, though not as potently as salvinorin A .
T27534 Herkinorin

BF3DNCA methyl ester

Herkinorin is an opioid analgesic and an analogue of the natural product Salvinorin A. herkinorin is a μ-opioid agonist with more than 100x higher μ-opioid affinity and 50x lower κ-opioid affinity compared to Salvinorin A. Herkinorin is a semi-synthetic c
T71491 Enadoline (Free Base)

Enadoline (Free Base) is a kappa-opioid receptor agonist; PD 129290 (CAM 570; CI 977) is the S,S(-)-enantiomer; PD 129289 (CAM 569) is the corresponding R,R(+)-enantiomer. In human studies, it produced visual distortions and feelings of dissociation, reminiscent of the effects of salvinorin A. It was studied as a potential analgesic, but abandoned because of the dose-limiting effects of dysphoria, which could be expected from a κ-opioid agonist. There was mention of its potential in treating com...

化合物

Salvinorin A Propionate
Cat.No: T38055
Synonym:
Target:
Herkinorin
Cat.No: T27534
Synonym: BF3DNCA methyl ester
Target:
Enadoline (Free Base)
Cat.No: T71491
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T23306 Salvinorin A

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Salvinorin A 是一种非含氮 κ-opioid 样物质选择性激动剂。

天然产物

Salvinorin A
Cat.No: T23306
Synonym:
Target: Opioid Receptor
TargetMol Loading
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