Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8409 |
SYN1143
RON-IN-1,AMG-1 |
c-Met/HGFR | Tyrosine Kinase/Adaptors |
SYN1143 (AMG-1) 是人 RON 和 c-Met 的有效抑制剂。体外激酶测定表明 SYN1143 对人 RON 和 c-Met 的 IC50 分别为 9 和 4 nmol/L。 | |||
T68408 |
AMG-1
|
||
AMG-1 is a specific CRAC channel inhibitor. AMG-1 blocks the function of effector T cells, but not regulatory T cells in vitro and it attenuates the progression and severity of EAE in vivo. |