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Targets Recommended: DUB

4

抑制剂 & 化合物

3

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T36970 STD1T

DUB Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination
STD1T 是一种具有选择性和有效性的脱泛素酶 USP2a 抑制剂,具有潜在的抗癌活性,可降低 HCT116 结肠和 MCF-7 乳腺癌细胞中的细胞周期蛋白 D1 蛋白水平。
T124703 Austdiol

T124598 Dihydrodeoxy-8-epiaustdiol

Dihydrodeoxy-8-epiaustdiol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124598,CAS号为 58957-07-6。
T68788 Ellipticine quinone

Ellipticine quinone, also known as NSC-383230, is a Drp1 inhibitor. rpitor1 and Drpitor1a inhibited the GTPase activity of Drp1 without inhibiting the GTPase of dynamin 1. Ellipticine quinone showed greater potency than the current std. Drp1 GTPase inhibitor, mdivi-​1, (IC50 for mitochondrial fragmentation are (0.06, and 10 μM, resp.)​. Ellipticine quinone suppressed lung cancer tumor growth in a mouse xenograft model. Ellipticine quinone also inhibited mitochondrial ROS prodn., prevented mi...

化合物

STD1T
Cat.No: T36970
Synonym:
Target: DUB
Austdiol
Cat.No: T124703
Synonym:
Target:
Dihydrodeoxy-8-epiaustdiol
Cat.No: T124598
Synonym:
Target:
Ellipticine quinone
Cat.No: T68788
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-01587 SULT2A1 Protein, Human, Recombinant (His)

hSTa,HST,ST2,ST2A1,STD,DHEAS,ST2A3,sulfotransferase...

Human E. coli
Hydroxysteroid sulfotransferase ( SULT2A1 ) is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar amon...
TMPH-03367 SOSTDC1 Protein, Rat, Recombinant (His & Myc)

Rat HEK293 Cells
Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling. SOSTDC1 Protein, Rat, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 24.6 kDa and the accession number is Q642G2.
TMPH-02885 SOSTDC1 Protein, Mouse, Recombinant (His & Myc)

Mouse E. coli
May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling. Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.

重组蛋白

SULT2A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01587
Species: Human
Expression System: E. coli
SOSTDC1 Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03367
Species: Rat
Expression System: HEK293 Cells
SOSTDC1 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02885
Species: Mouse
Expression System: E. coli
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