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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

3

抑制剂 & 化合物

2

天然产物

10

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T36539	Nocardamine
	Nocardamine is a ferrioxamine siderophore that has been found inStreptomycesand has diverse biological activities.1,2,3,4It chelates iron in a chrome azurol S assay (IC50= 9.9 μM).1Nocardamine inhibitsM. smegmatisandM. bovisbiofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron.2It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC50s = 6, 18, 12, and 14 μM, respectively).3Nocardamine also induces morphological changes in BM-N4 insect cells.4 1.Lo...
T37564	C4 Ceramide (d18:1/4:0) C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0)
	C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. [1] [2] [3] It inhibits IL-4 production by 16% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. [1] C4 Ceramide is cytotoxic to SK-BR-3 and MCF-7/Adr breast cancer cells (IC50s = 15.9 and 19.9 μM, respectively). [2] C4 Ceramide also increases maturation and stability of cystic fibrosis transmembrane conductance regulator (CFTR) proteins bearing...
T35683	2-deoxy-D-Glucose-13C6 2-deoxy-D-Glucose-13C6
	2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate.32-deoxy-D-Glucose (16 mM) induces apoptosis in SK-BR-3 cells, as well as inhibits the growth of 143B oste...

化合物

Cat.No: T36539

C4 Ceramide (d18:1/4:0)

Cat.No: T37564

Synonym: C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0)

2-deoxy-D-Glucose-13C6

Cat.No: T35683

Synonym: 2-deoxy-D-Glucose-13C6

Cat. No.	Product Name	Target	Signaling Pathways
TN2977	3-O-trans-p-Coumaroyltormentic acid	Caspase; Antifection	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	3-O-(E)-p-coumaroyl tormentic acid may be promising lead compound for developing an effective drug for treatment of leukemia, it induces apoptotic cell death in human leukemia (HL60) via mainly mitochondrial pathway by, at least in part, Topo I inhibition. 3-O-trans-p-coumaroyltormentic acid shows cytotoxicity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro, the IC50 values of 13.72, 14.29,14.61, 14.04 uM, respectively. 3beta-O-cis-p-Coumaroyltormentic acid, an...
T36954	Nemorosone
	Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma cells (IC50s = 3.1-6.3 μM), including several drug-resistant clones, but not MRC-5 human embryonic fibroblasts (IC50 = >40 μM).2 It increases DNA fragmentation in LAN-1 cells in a dose-dependent manner, and decreases N-Myc protein levels and phosphorylation of ERK1/2 by MEK1/2. Nem...

天然产物

3-O-trans-p-Coumaroyltormentic acid

Cat.No: TN2977

Target: Caspase, Antifection

Cat.No: T36954

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05579	PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated PRR1,ED4,PVRR,nectin-1,OFC7,SK-12,CD111,CL...	Human	HEK293 Cells
	PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1.
TMPK-00313	Nectin-1 Protein, Human, Recombinant (His & Avi), Biotinylated HIgRPVRR,OFC7,CLPED1,SK-12,MGC142031,HIgR,...	Human	HEK293 Cells
	Nectin-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 36.9 kDa and the accession number is Q15223-1.
TMPY-01572	PVRL1/NECTIN1 Protein, Human, Recombinant (His) HVEC,ED4,PRR1,PVRR1,nectin-1,HIgR,poliovirus receptor-relate...	Human	HEK293 Cells
	PVRL1/NECTIN1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.4 kDa and the accession number is Q15223-1.
TMPK-00312	Nectin-1 Protein, Human, Recombinant (His & Avi) PVRR1,HIgRPVRR,PVRL1,CLPED1,MGC142031,SK-12	Human	HEK293 Cells
	Nectin-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 36.9 kDa and the accession number is Q15223.
TMPY-01571	PVRL1/NECTIN1 Protein, Human, Recombinant (hFc) HV1S,ED4,poliovirus receptor-related 1 (herpesvirus entry me...	Human	HEK293 Cells
	PVRL1/NECTIN1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1.
TMPY-02642	UBE2W Protein, Human, Recombinant (His) UBC16,UBC-16,ubiquitin-conjugating enzyme E2W (putative)	Human	E. coli
	Ubiquitin-conjugating enzymes, also known as UBE2W, E2 enzymes and more rarely as ubiquitin-carrier enzymes, perform the second step of protein ubiquitination. The modification of protein with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2W is a member of th...
TMPY-00031	Neuregulin-1/NRG1 Protein, Human, Recombinant (His) HRG1,GGF2,HRG,NDF,MSTP131,HRGA,GGF,neuregulin 1,HGL,SMDF,ARI...	Human	HEK293 Cells
	Neuregulin-1/NRG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is Q02297-12.
TMPY-03797	Neurofascin Protein, Human, Recombinant (His) neurofascin,NF,NRCAML	Human	HEK293 Cells
	Neurofascin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 104.4 kDa and the accession number is O94856-12.
TMPY-04620	Neurofascin Protein, Human, Recombinant (hFc) neurofascin,NRCAML,NF	Human	HEK293 Cells
	Neurofascin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 130 kDa and the accession number is O94856-12.
TMPY-00479	Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc) ARIA,neuregulin 1,GGF2,MSTP131,GGF,MST131,HGL,NDF,SMDF,HRG1,...	Human	HEK293 Cells
	Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.5 kDa and the accession number is Q02297-12.

重组蛋白

PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated

Cat.No: TMPY-05579

Species: Human

Expression System: HEK293 Cells

Nectin-1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00313

Species: Human

Expression System: HEK293 Cells

PVRL1/NECTIN1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01572

Species: Human

Expression System: HEK293 Cells

Nectin-1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00312

Species: Human

Expression System: HEK293 Cells

PVRL1/NECTIN1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01571

Species: Human

Expression System: HEK293 Cells

UBE2W Protein, Human, Recombinant (His)

Cat.No: TMPY-02642

Species: Human

Expression System: E. coli

Neuregulin-1/NRG1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00031

Species: Human

Expression System: HEK293 Cells

Neurofascin Protein, Human, Recombinant (His)

Cat.No: TMPY-03797

Species: Human

Expression System: HEK293 Cells

Neurofascin Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04620

Species: Human

Expression System: HEK293 Cells

Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00479

Species: Human

Expression System: HEK293 Cells

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