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Cat. No. Product Name Target Signaling Pathways
T29067 Upacicalcet

PLS-240,SK-1403,AJT-240

Calcium Channel Membrane transporter/Ion channel; Metabolism
Upacicalcet (AJT-240) 是一种静脉内拟钙剂,是一种可用于人血液透析的 SHPT, 通过直接作用于甲状旁腺细胞膜钙敏感受体来抑制过量的甲状旁腺激素 (PTH) 分泌,从而降低血液中的 PTH 水平。 3 Upacicalcet 是钙敏感受体的正变构调节剂,可预防大鼠腺嘌呤诱导的继发性甲状旁腺功能亢进模型中的血管钙化和骨骼疾病。
T61232 (Rac)-Upacicalcet

(Rac)-Upacicalcet is a racemate of Upacicalcet, which serves as an intravenous calcimimetic agent. Upacicalcet acts by directly targeting calcium-sensing receptors on parathyroid cell membranes, effectively suppressing the release of excessive parathyroid hormone (PTH) and reducing blood PTH levels. This compound holds the potential for researching secondary hyperparathyroidism (SHPT) [1].
T39444 Upacicalcet sodium

Upacicalcet (sodium) is an intravenous calcimimetic agent that acts directly on parathyroid cell membrane calcium-sensing receptors to suppress excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels. It is indicated for the research of secondary hyperparathyroidism (SHPT).
T29067L Upacicalcet HCl

Upacicalcet HCl(1333218-50-0 Free base)

CaSR GPCR/G Protein
Upacicalcet HCl 是一种静脉内拟钙剂,通过直接作用于甲状旁腺细胞膜钙敏感受体来抑制过量的甲状旁腺激素 (PTH) 分泌,从而降低血液中的 PTH 水平。Upacicalcet HCl 可用于治疗血液是一种新型继发性甲状旁腺功能亢进化合物,靶向钙敏感受体的氨基酸结合位点。

化合物

Upacicalcet
Cat.No: T29067
Synonym: PLS-240,SK-1403,AJT-240
Target: Calcium Channel
(Rac)-Upacicalcet
Cat.No: T61232
Synonym:
Target:
Upacicalcet sodium
Cat.No: T39444
Synonym:
Target:
Upacicalcet HCl
Cat.No: T29067L
Synonym: Upacicalcet HCl(1333218-50-0 Free base)
Target: CaSR
TargetMol Loading
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