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Targets Recommended: Phosphatase

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抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T9744 MP07-66

Phosphatase Metabolism
MP07-66 是 FTY720 的一种类似物,没有免疫抑制作用。MP07-66通过破坏 SET-PP2A 复合物导致PP2A 重新激活。MP07-66在慢性淋巴细胞白血病中显示出良好的抗肿瘤作用。

化合物

MP07-66
Cat.No: T9744
Synonym:
Target: Phosphatase
Cat. No. Product Name Species Expression System
TMPY-01584 PR-Set7 Protein, Human, Recombinant

SET8,SET07,PR-Set7,S...

Human E. coli
KMT5A (known as PR-Set7/9, SETD8 and SET8), a member of the SET domain containing methyltransferase family specifically targeting H4K20 for methylation, has been implicated in multiple biological processes. Inhibition of KMT5A attenuated proliferation and induced apoptosis. Elevated KMT5A expression was significantly correlated with extrathyroidal extension, lymph node metastasis and advanced pathological stage of papillary thyroid cancer. KMT5A may be a novel oncogenic factor, specifically a re...

重组蛋白

PR-Set7 Protein, Human, Recombinant
Cat.No: TMPY-01584
Species: Human
Expression System: E. coli
TargetMol Loading
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