1
7
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T23444 |
TCS 1105
N-(4-fluorobenzyl)-2-(1H-indol-3-yl)-2-oxoacetamide |
Others | Others |
TCS 1105是一种GABAA 苯并二氮卓受体(BZR)配体。TCS 1105阻断Sema3A 诱导的轴突生长锥塌陷。TCS 1105能减少小鼠的焦虑样行为,增强攻击性行为和社会支配力。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04625 |
SEMA3A Protein, Mouse, Recombinant (His)
SemD,Semad,Hsema-I,SEMA1,coll-1,<... |
Mouse | HEK293 Cells |
SEMA3A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.6 kDa and the accession number is A0A803Z7F8. | |||
TMPY-00124 |
SEMA3A Protein, Human, Recombinant (hFc)
sema domain, immunoglobulin domain (Ig), short basi... |
Human | HEK293 Cells |
SEMA3A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.7 kDa and the accession number is Q14563. | |||
TMPJ-00383 |
SEMA3A Protein, Human, Recombinant (His & Flag)
Hsema-III,SemD,SEMA3A,Sema |
Human | HEK293 Cells |
emaphorin-3A is a secreted protein which belongs to the semaphorin family. Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 500 aa Sema domain.This protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with s... | |||
TMPY-02360 |
SEMA3A Protein, Mouse, Recombinant (hFc)
Semad,Hsema-I,coll-1,sema domain,... |
Mouse | HEK293 Cells |
SEMA3A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.7 kDa and the accession number is O08665. | |||
TMPH-03369 |
SEMA3A Protein, Rat, Recombinant (His)
|
Rat | E. coli |
May be involved in guiding growing axons towards their targets by forming a molecular boundary that instructs axons to engage in the formation of specific nerve tracts. Binds to neuropilin. Involved in the development of the olfactory system and in neuronal control of puberty. SEMA3A Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 90.6 kDa and the accession number is Q63548. | |||
TMPH-01874 |
Plexin-A4 Protein, Human, Recombinant (His)
|
Human | E. coli |
Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. Plexin-A4 Protein, Human, Recombinant (His) is expressed in... | |||
TMPH-01226 |
CRMP1 Protein, Human, Recombinant
ULIP3,Collapsin response mediator protein 1,CRMP1,Dihydropyr... |
Human | E. coli |
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone. Involved in invasive growth and cell migration. May participate in cytokinesis. CRMP1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted mole... |