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2
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10618 |
Broflanilide
|
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Broflanilide 是昆虫抗狄氏剂 GABA 受体拮抗剂,可代谢为 Desmethyl-Broflanilide,抑制斜纹夜蛾 RDL GABAR,IC50值为 1.3 nM。 | |||
T82357 | GABA receptor Antagonist 1 | GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
GABA receptorAntagonist 1 (compound 7w) 在抑制PxRDL1GABAR方面具有高特异性,IC50为7.08 nmol/L。针对P. xylostella、S. frugiperda、S. exigua和S. litura的杀虫活性显著,相应的LC50值分别为0.09、0.84、0.87和0.68 mg/L。此化合物对蜜蜂的急性毒性为中等(48小时,LD50=2.22μg/成虫),而对斑马鱼的急性毒性较低(LC50: 42.4mg/L)。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11680 |
Isoasatone A
|
P450 | Metabolism |
Isoasatone A 是一种具有抗虫作用的天然产物,分离自Heterotropa takaoiM。它作用于细胞色素 P450 单加氧酶和谷胱甘肽转移酶,产生抗S. litura 作用。 | |||
TN4223 |
Homopterocarpin
|
Antifection | Microbiology/Virology |
Homopterocarpin and Pterocarpus extract offer gastroprotection against indomethacin- induced ulcer by antioxidative mechanism and the modulation of gastric homeostasis, homopterocarpin may be responsible for, or contribute to the antiulcerogenic property |