Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12790 |
Guadecitabine sodium
SGI-110 sodium,S-110 sodium |
DNA Methyltransferase | Chromatin/Epigenetic |
Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) . | |||
T37847 |
Zonisamide-13C2,15N
Zonisamide-13C2,15N |
||
Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium... |