Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16779 |
Rodatristat ethyl
RVT-014,KAR5585,RVT-1201 |
5-HT Receptor; Hydroxylase | GPCR/G Protein; Metabolism; Neuroscience |
Rodatristat ethyl (KAR5585) 是一种首新型具有口服活性和有效性的 tryptophan hydroxylase 1 (TPH1) 抑制剂,低浓度下可显著降低 5-hydroxytryptamine (5-HT) 的水平并降低肺动脉高压 (PAH), |