Cat. No. | Product Name | Target | Signaling Pathways |
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T1734L |
Rizatriptan
MK 462 free base,Risatriptan |
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Rizatriptan is an agonist of the serotonin-1b and serotonin-1d receptor. | |||
T1512 |
Rizatriptan benzoate
苯甲酸利扎曲坦,MK-462 Benzoate |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Rizatriptan benzoate (MK-462 Benzoate) 是 5-HT1激动剂,通过选择性结合并激活血清素 (5-HT) 1B 受体和 5-HT 1D 受体,从而缓解偏头痛。 | |||
T35882 |
Rizatriptan N-oxide
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Rizatriptan N-oxide is a potential impurity found in commercial preparations of rizatriptan.1It is a degradation product formed under oxidative conditions. | |||
T70408 |
Rizatriptan sulfate
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Rizatriptan sulfate is a selective serotonin 5-HTID receptor agonist derived from tryptamine. | |||
T71211 |
Rizatriptan-d6 benzoate salt
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Rizatriptan-d6 is intended for use as an internal standard for the quantification of rizatriptan by GC- or LC-MS. Rizatriptan is an agonist of the serotonin receptor subtypes 5-HT1B and 5-HT1D. It is selective for 5-HT1B and 5-HT1D receptors over 5-HT1A receptors. Rizatriptan induces vasoconstriction in isolated human middle meningeal arteries. In vivo, rizatriptan reduces head grooming, the number of oculotemporal strokes, eye blinking, and one-eye closures in a Cacna1a mutant transgenic mou... | |||
T70407 |
cemadotin free base
LU103793 free base |
Microtubule Associated | Cytoskeletal Signaling |
Cemadotin free base(LU103793 free base) 是一种新型的抗限定性肽 ,是一种新型的抗有丝分裂肽 ,是Dolastatin 15的类似物 。Dolastatin 15是一种天然存在的细胞毒肽,可阻断有丝分裂并抑制微管(管蛋白),Ki 为1μM。Cemadotin 用于研究抗癌。 | |||
T71209 |
CGS 12066A
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CGS 12066A is a drug which acts as a potent and selective agonist for the 5-HT1B receptor with lower affinity for the three 5-HT₂ receptor subtypes. It is used for studying the role of the 5-HT1B receptor in various processes including perception of pain and the sleep-wake cycle. |