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Search Results for " rifamycin "

15

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T21225	Rifamycin Rifocin,Rifamycin SV
	Rifamycin, a natural antibiotic, inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis, leading to the block of RNA-polymerase transcription initiation.
T28538	Rifamycin SV
	Rifamycin SV, a natural antibiotic, blocks RNA-polymerase transcription initiation, modulating ß2m aggregation; inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis.
T19118	3-Formyl rifamycin	Others	Others
	3-Formyl rifamycin is an intermediate of Rifampicin.
T65421	Rifamycin O
	Rifamycin O 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65421，CAS号为 14487-05-9。
T1629	Rifapentine MDL473,Rifapentina,Rifapentinum,DL 473,利福喷丁,Priftin,Cyclopentylrifampicin	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Rifapentine (Rifapentinum) 是可用于肺结核的抗生素。
T1154	Rifaximin	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Rifaximin 是一种胃肠道选择性抗生素，与细菌 DNA 依赖性 RNA 聚合酶的 β 亚基结合，抑制细菌 RNA 合成。与革兰氏阴性菌（MIC：8-50 毫克/毫升）相比，它对革兰氏阳性菌株（MIC：0.03-5 毫克/毫升）的敏感性更高。
T26084	Rifamexil
	Rifamexil is a rifamycin (antibiotic produced naturally by the bacterium Amycolatopsis rifamycinica) derivative.
T26062	Reprimun
	Reprimun has a large spectrum antibiotic activity that contains an oxyminomethyl rifamycin-SV derivative as the active substance.
T69384	AF-013
	AF-013 is a rifamycin derivative -- specifically an O-n-octyloxime of 3-formylrifamycin SV -- which acts as an inhibitor of nucleic acid polymerases.
T26083	Rifametane Rifametanum
	Rifametane is a new semi-synthetic rifamycin, an antibiotic produced naturally by the bacterium Amycolatopsis rifamycinica.
T34900	Tolypomycin R B-2847-R
	Tolypomycin R is a rifamycin derivative.
T71199	CGP7040
	CGP7040 is a rifamycin analogue, is a protein 50S ribosomal subunit inhibitor that was being developed by Novartis.
T11062	dmDNA31	Others	Others
	dmDNA31 is a rifamycin antibiotic that can inhibit the DNA-dependent RNA polymerase of bacteria and has strong bactericidal activity against Staphylococcus aureus.
T35706	25-Desacetyl Rifampicin
	25-Desacetyl rifampicin is a major active metabolite of the rifamycin antibiotic rifampicin .125-Desacetyl rifampicin is active againstM. smegmatis(MIC99= 2.66 μM). 1.Kigondu, E.M., Njoroge, M., Singh, K., et al.Synthesis and synergistic antimycobacterial screening of chlorpromazine and its metabolitesMed. Chem. Commun.5502-506(2014)
T16749	Rifalazil 利福拉齐,KRM-1648,ABI-1648	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Rifalazil is a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase. Rifalazil is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis (MIC: 0.00025 to 0.0025 μg/ml).

化合物

Cat.No: T21225

Synonym: Rifocin,Rifamycin SV

Cat.No: T28538

3-Formyl rifamycin

Cat.No: T19118

Target: Others

Cat.No: T65421

Cat.No: T1629

Synonym: MDL473,Rifapentina,Rifapentinum,DL 473,利福喷丁,Priftin,Cyclopentylrifampicin

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T1154

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T26084

Cat.No: T26062

Cat.No: T69384

Cat.No: T26083

Synonym: Rifametanum

Cat.No: T34900

Synonym: B-2847-R

Cat.No: T71199

Cat.No: T11062

Target: Others

25-Desacetyl Rifampicin

Cat.No: T35706

Cat.No: T16749

Synonym: 利福拉齐,KRM-1648,ABI-1648

Target: DNA/RNA Synthesis

Cat. No.	Product Name	Target	Signaling Pathways
T5003	Rifamycin sodium Rifamycin sodium salt,利福霉素钠	Antibacterial; Antibiotic	Microbiology/Virology
	Rifamycin sodium (Rifamycin sodium salt) salt 是从地中海曲霉或其突变体的发酵中分离出来的一种安沙霉素抗生素家族。它对革兰氏阳性菌和某些革兰氏阴性菌有抗生素活性。
T8347	Rifamycin S	Reactive Oxygen Species; ROS; Antibacterial; Antibiotic	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Rifamycin S 是一种 DNA 依赖性 RNA 聚合酶抑制剂，是一种醌和一种针对革兰氏阳性细菌的抗生素试剂。它是涉及两个电子的可逆氧化还原系统的氧化形式。它能产生活性氧并抑制微粒体脂质过氧化，可研究肺结核和麻风病。
T0681	Rifampicin Rifamycin AMP,利福平,Rimactane,Rifampin	Influenza Virus; DNA/RNA Synthesis; Antibacterial; Antibiotic; Antifection	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Rifampicin (Rifamycin AMP) 是广谱抗生素，可抵抗细菌病原体以及具有抗流感病毒活性。

天然产物

Rifamycin sodium

Cat.No: T5003

Synonym: Rifamycin sodium salt,利福霉素钠

Target: Antibacterial, Antibiotic

Cat.No: T8347

Target: Reactive Oxygen Species, ROS, Antibacterial, Antibiotic

Cat.No: T0681

Synonym: Rifamycin AMP,利福平,Rimactane,Rifampin

Target: Influenza Virus, DNA/RNA Synthesis, Antibacterial, Antibiotic, Antifection

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