Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37422 |
Ras Inhibitory Peptide
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Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence PVPPR, which corresponds to a region within human Sos1 that interacts with an SH3 domain of Grb2. It specifically blocks the interaction of the GEF with Grb2, preventing an interaction ... | |||
T37422L |
Ras Inhibitory Peptide acetate
Ras Inhibitory Peptide acetate(159088-48-9 Free base) |
Ras | GPCR/G Protein; MAPK |
Ras Inhibitory Peptide acetate 是一种参与 Ras 依赖性信号通路的肽,Ras 在致癌受体引发的人类癌症中起重要作用。 | |||
TP2358 |
KRPEP-2D acetate
|
Raf | MAPK |
KRPEP-2D acetate 被鉴定为针对 K-Ras 的 G12D 突变体的 K-Ras(G12D) 选择性抑制肽,K-Ras 是 Ras 蛋白家族的关键成员和有吸引力的癌症治疗靶点。 |