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Targets Recommended: HBV DNA/RNA Synthesis

2

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T0353 Osalmid

Oxaphenamide,4'-Hydroxysalicylanilide,羟苯水杨胺,柳胺酚

HBV; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
Osalmid (Oxaphenamide) 是一种利胆药物,通过靶向核糖核苷酸还原酶小亚基 M2 来抑制核糖核苷酸还原酶的活性,IC50值为8.23 μM。
T81251 rTRD01

rTRD01为TDP-43配体,与TDP-43的RRM1和RRM2结构域结合(Kd=89 uM,TDP-43102-269)。该化合物能够削弱TDP-43与与疾病相关的c9orf72基因的六核苷酸RNA的交互作用,可作为神经退行性疾病研究的工具。

化合物

Osalmid
Cat.No: T0353
Synonym: Oxaphenamide,4'-Hydroxysalicylanilide,羟苯水杨胺,柳胺酚
Target: HBV, DNA/RNA Synthesis
rTRD01
Cat.No: T81251
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00937 RRM2 Protein, Human, Recombinant (His)

RRM2,RR2,Ribonucleotide Reductase...

Human HEK293 Cells
Ribonucleoside-Diphosphate Reductase Subunit M2 (RRM2) belongs to the ribonucleoside diphosphate reductase small chain family. The reductase of RRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. RRM2 supplies the precursors essential for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Phosphorylation on Ser-20 relieves the in...
TMPH-02084 SRRM2 Protein, Human, Recombinant (His & Myc)

Human Baculovirus Insect Cells
SRRM2 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.

重组蛋白

RRM2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00937
Species: Human
Expression System: HEK293 Cells
SRRM2 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02084
Species: Human
Expression System: Baculovirus Insect Cells
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