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Cat. No. Product Name Target Signaling Pathways
T60187 RP-6685

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
RP-6685, a highly potent and selective inhibitor of DNA polymerase theta (Polθ), manifests remarkable oral activity. With an IC 50 value of 5.8 nM in the PicoGreen assay, RP-6685 effectively hinders the enzymatic activity of Polθ. In addition, it demonstrates significant antitumor efficacy as observed in a mouse tumor xenograft model [1].

化合物

RP-6685
Cat.No: T60187
Synonym:
Target: DNA/RNA Synthesis
TargetMol Loading
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