Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16755 |
RIPK-IN-4
|
TNF | Apoptosis |
RIPK-IN-4 is an effective and selective inhibitor of RIPK2. It also has excellent oral bioavailability (IC50: 3 nM). | |||
T12730 |
RIPK1-IN-4
|
RIP kinase | Apoptosis; NF-κB |
RIPK1-IN-4 是有效的 II 型激酶受体相互作用蛋白1 (RIP1) 激酶抑制剂,并且与 DL1-out 无活性形式的 RIP1 结合。RIPK1-IN-4抑制 RIP1 和 ADP-Glo 激酶,IC50 分别是 16 nM 和 10 nM。 |