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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35328 |
H-1152 dihydrochloride
H-1152 2HCl,H-1152 dihydrochloride |
ROCK | Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells |
H-1152 dihydrochloride (H-1152 2HCl) 是 Rho 相关蛋白激酶 (ROCK) 的特异性抑制剂,IC50 为 12 nM,Ki 为 1.6 nM。 H-1152 dihydrochloride 抑制 PKA、PKC、PKG、Aurora A 和 CaMKII,IC50 值分别为 3.03 μM、5.68 μM、0.360 μM、0.745 μM 和 0.180 μM。 | |||
T7552 |
H-1152
|
ROCK | Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells |
H-1152 是一种膜通透的选择性ROCK 抑制剂,Ki 为 1.6 nM,对ROCK2的IC50为 12 nM。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01958 |
RhoA Protein, Human, Recombinant (His)
ras homolog family member A,ARHA,RHO12, |
Human | Baculovirus Insect Cells |
Transforming protein RhoA, also known as Rho cDNA clone 12, Ras homolog gene family member A, RHOA and ARH12, is a cell membrane and cytoplasm protein that belongs to the small GTPase superfamily and Rho family. The Rho family of small GTPases plays a key role in the dynamic regulation of the actin cytoskeleton that underlies various important cellular functions such as shape changes, migration, and polarity. RHOA / ARH12 is part of a larger family of related proteins known as the Ras superfamil... | |||
TMPH-02041 |
ARHGEF12 Protein, Human, Recombinant (His)
ARHGEF12,KIAA0382,Rho guanine nucleotide e... |
Human | E. coli |
ARHGEF12 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPY-04620 |
Neurofascin Protein, Human, Recombinant (hFc)
neurofascin,NRCAML,NF |
Human | HEK293 Cells |
Neurofascin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 130 kDa and the accession number is O94856-12. | |||
TMPY-00479 |
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
ARIA,neuregulin 1,GGF2,MSTP131,GGF,MST131,HGL,NDF,SMDF,HRG1,... |
Human | HEK293 Cells |
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.5 kDa and the accession number is Q02297-12. | |||
TMPY-03797 |
Neurofascin Protein, Human, Recombinant (His)
neurofascin,NF,NRCAML |
Human | HEK293 Cells |
Neurofascin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 104.4 kDa and the accession number is O94856-12. | |||
TMPY-00031 |
Neuregulin-1/NRG1 Protein, Human, Recombinant (His)
HRG1,GGF2,HRG,NDF,MSTP131,HRGA,GGF,neuregulin 1,HGL,SMDF,ARI... |
Human | HEK293 Cells |
Neuregulin-1/NRG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is Q02297-12. | |||
TMPY-02642 |
UBE2W Protein, Human, Recombinant (His)
UBC16,UBC-16,ubiquitin-conjugating enzyme E2W (putative) |
Human | E. coli |
Ubiquitin-conjugating enzymes, also known as UBE2W, E2 enzymes and more rarely as ubiquitin-carrier enzymes, perform the second step of protein ubiquitination. The modification of protein with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2W is a member of th... |