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14

抑制剂 & 化合物

20

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T61300	RBP4 inhibitor 1
	RBP4 inhibitor 1 (compound 43b) is an orally active and potent inhibitor of retinol-binding protein 4 (RBP4), exhibiting IC50 values of 28 nM and 110 nM for human and mouse RBP4, respectively. It effectively reduces blood RBP4 levels in mice, providing a long-lasting effect [1].
T62141	RBP4 ligand-1
	RBP4 ligand-1 是一种视黄醇结合蛋白 4 (RBP4) 的非视黄醇配体。RBP4 ligand-1 在放射配体结合检测和 FRET 检测中对 hRBP4SPAIC50 和 RBP4–TTR FRET IC50值分别为 0.23±0.11 和 0.13±0.12 μM。
T35566	RBPJ Inhibitor-1 RIN1	Gamma-secretase	Neuroscience; Proteases/Proteasome; Stem Cells
	RBPJ Inhibitor-1 (RIN1)是一个 RBPJ 抑制剂，它能阻断 RBPJ 与 SHARP 的功能性相互作用。RBPJ Inhibitor-1可抑制依赖于 NOTCH 的肿瘤细胞增殖。
TP1120L	IRBP acetate(211426-18-5 free base) Interphotoreceptor Retinoid Binding Protein Fragment IRBP	Others	Others
	IRBP acetate(211426-18-5 free base) (Interphotoreceptor Retinoid Binding Protein Fragment IRBP) 是一种含有 20 个残基的肽，是一种主要的致病表位。它存在于间质视觉色素结合蛋白肽（IRBP 161-180）的第一个同源重复序列中，可诱导葡萄膜炎后（EAU）。
T34271	RBPI-3
	RBPI-3 is a canonical poly(ADP-ribose) glycohydrolase.
T83700	IRBP (651-670) (human) TFA IRBP651-670,Interphotoreceptor Retinoid-Binding Protein (651-670)
	IRBP651-670（Interphotoreceptor retinoid-binding protein (651-670)）是IRBP（亦称为retinoid-binding protein 3）的肽段，参与色素再生，通过将视黄醇和视黄醛从光感受细胞传输到视网膜色素上皮。在C57BL/6小鼠中，利用IRBP651-670诱导自身免疫性葡萄膜炎，这些小鼠携带H-2b单体型。用IRBP651-670（300 µg/动物）免疫增加了小鼠眼部IL-1β、IL-6、IL-17、TNF-α和IFN-γ水平，免疫细胞浸润及光感受器损伤。
TP1118	IRBP(668-687) (TFA) (1977546-93-2 free base) IRBP(668-687) (TFA),Interphotoreceptor retinoid-binding protein(668-687) TFA
	Interphotoreceptor retinoid-binding protein(668-687) TFA is the 668-687 amino acid residue of human Interphotoreceptor retinoid binding protein(IRBP), which can induce uveitis.
TP1749	IRBP (1-20), human
	IRBP (1-20), human is the 1-20 fragment of interphotoreceptor retinoid binding protein (IRBP).This peptide is a 1 to 20 amino acid fragment of the interphotoreceptor retinoid binding protein (IRBP). IRBP is a 140-kDa glycolipoprotein residing in the inter
T82051	IRBP derived peptide, R16
	R16，一种IRBP衍生肽，具有生物活性。该肽可在易感动物品系中诱导实验性自身免疫性葡萄膜炎（EAU）。
TP1120	Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) IRBP,Interphotoreceptor Retinoid Binding Protein Fragment IRBP
	Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) is a 20-residue peptide, which is a major pathogenic epitope. It exists in the first homologous repeat of interstitial visual pigment Binding Protein peptide (IRBP 161-180) and can induce post-uv
T15585	IRBP(668-687) (TFA) Interphotoreceptor retinoid-binding protein(668-687) TFA	Others	Others
	Interphotoreceptor retinoid-binding protein TFA is the amino acid residue 668 to 687 of human interphotoreceptor retinoid-binding protein (IRBP). It also induces uveitis.
T78008	IRBP (1-20), human TFA
	IRBP (1-20), human TFA 是含有H-2b单倍型主要表位的化合物。在H-2b基因型的小鼠中，IRBP (1-20), human TFA 能够诱导实验性自身免疫性葡萄膜视网膜炎（EAU）。
T83681	IRBP (1-20) (human, rat) TFA IRBP1-20,Interphotoreceptor Retinoid-Binding Protein (1-20)
	IRBP1-20（1-20）是IRBP的一个十二肽片段，亦称视黄醇结合蛋白3，负责运输视锥细胞中的视黄醇和视黄醛至视网膜色素上皮，参与色素再生。在携带H-2b等位基因型的C57BL/6小鼠中，IRBP1-20用于诱导自身免疫性葡萄膜视网膜炎。IRBP1-20（3 µM）能增加初级小鼠脾淋巴细胞分泌IL-4、IL-5和IL-6的水平。用IRBP1-20免疫并再次挑战，可增加IFN-γ缺乏小鼠的耳部肿胀、眼部血管炎症、免疫细胞浸润和视锥细胞层损伤，以及视网膜脱落。
T82050	IRBP derived peptide, R16 acetate
	R16 acetate，作为IRBP（光感受器间视黄酸结合蛋白）源的生物活性肽段，能在敏感的动物模型中诱导实验性自身免疫性葡萄膜炎（EAU）。

化合物

RBP4 inhibitor 1

Cat.No: T61300

RBP4 ligand-1

Cat.No: T62141

RBPJ Inhibitor-1

Cat.No: T35566

Synonym: RIN1

Target: Gamma-secretase

IRBP acetate(211426-18-5 free base)

Cat.No: TP1120L

Synonym: Interphotoreceptor Retinoid Binding Protein Fragment IRBP

Target: Others

Cat.No: T34271

IRBP (651-670) (human) TFA

Cat.No: T83700

Synonym: IRBP651-670,Interphotoreceptor Retinoid-Binding Protein (651-670)

IRBP(668-687) (TFA) (1977546-93-2 free base)

Cat.No: TP1118

Synonym: IRBP(668-687) (TFA),Interphotoreceptor retinoid-binding protein(668-687) TFA

IRBP (1-20), human

Cat.No: TP1749

IRBP derived peptide, R16

Cat.No: T82051

Interphotoreceptor Retinoid Binding Protein Fragment (IRBP)

Cat.No: TP1120

Synonym: IRBP,Interphotoreceptor Retinoid Binding Protein Fragment IRBP

IRBP(668-687) (TFA)

Cat.No: T15585

Synonym: Interphotoreceptor retinoid-binding protein(668-687) TFA

Target: Others

IRBP (1-20), human TFA

Cat.No: T78008

IRBP (1-20) (human, rat) TFA

Cat.No: T83681

Synonym: IRBP1-20,Interphotoreceptor Retinoid-Binding Protein (1-20)

IRBP derived peptide, R16 acetate

Cat.No: T82050

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01567	RBP4 Protein, Mouse, Recombinant (His) Rbp-4,retinol binding protein 4, plasma	Mouse	HEK293 Cells
	RBP4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.8 kDa and the accession number is Q00724.
TMPJ-00084	RBP4 Protein, Human, Recombinant Retinol-Binding Protein 4,Plasma Retinol-Binding Protein,P	Human	E. coli
	Retinol Binding Protein 4 (RBP4) is a member of the Lipocalin family and in the blood. RBP4 is the specific vector for retinol. RBP4 is expressed and secreted by adipose tissue, and is associated with insulin resistance. RBP4 delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin to prevents its loss by filtration through the kidney glomeruli. Defects in RBP4 cause retinol-binding protein deficiency and can cause night vi...
TMPJ-01063	RBP5 Protein, Human, Recombinant Retinol-binding protein 5,CRBP-III,Cellular retinol...	Human	E. coli
	RBP5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14 KDa and the accession number is P82980.
TMPY-04076	RBP5 Protein, Human, Recombinant (His) CRBPIII,retinol binding protein 5,CRBP3,	Human	E. coli
	RBP5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.2 kDa and the accession number is P82980.
TMPJ-00992	RBP2 Protein, Human, Recombinant CRBP-II,RBP2,CRBP2,Cellular retin...	Human	E. coli
	RBP2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15-17 KDa and the accession number is P50120.
TMPY-00907	RBP4 Protein, Human, Recombinant (His) RDCCAS,retinol binding protein 4, plasma	Human	HEK293 Cells
	RBP4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23 kDa and the accession number is P02753.
TMPJ-00829	RBP3 Protein, Human, Recombinant (His) Retinol-binding protein 3,Interstitial retinol-binding prote...	Human	E. coli
	RBP3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 38 and 75-80 KDa and the accession number is P10745.
TMPJ-00814	RBP1 Protein, Human, Recombinant Cellular retinol-binding protein I,CRBP-I,RBP	Human	E. coli
	RBP1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14 KDa and the accession number is P09455.
TMPY-01549	CRABP2 Protein, Human, Recombinant (His) RBP6,cellular retinoic acid binding protein 2,CRABP...	Human	E. coli
	CRABP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16.5 kDa and the accession number is P29373.
TMPY-03864	CRABP1 Protein, Human, Recombinant CRABP,CRABP-I,RBP5,cellular retinoic acid binding p...	Human	E. coli
	CRABP1 is a specific binding protein for a vitamin A family member. It is thought that CRABP1 plays an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. It forms a beta-barrel structure which accommodates hydrophobic ligands in its interior.
TMPY-04056	RBP7 Protein, Human, Recombinant (His) CRBP4,CRBPIV,retinol binding protein 7, ce...	Human	E. coli
	RBP7 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.8 kDa and the accession number is Q96R05.
TMPY-02861	RBP4 Protein, Canine, Recombinant (His) retinol binding protein 4, plasma	Canine	HEK293 Cells
	RBP4 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.4 kDa and the accession number is F1PQI4.
TMPY-03591	RBP4 Protein, Cynomolgus, Recombinant (His) retinol binding protein 4, plasma	Cynomolgus	HEK293 Cells
	RBP4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.6 kDa.
TMPY-02834	RBP4 Protein, Canine, Recombinant (hFc) retinol binding protein 4, plasma	Canine	HEK293 Cells
	RBP4 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is F1PQI4.
TMPY-01611	RBP4 Protein, Rat, Recombinant (His) retinol binding protein 4, plasma	Rat	HEK293 Cells
	RBP4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.8 kDa and the accession number is B2RZC1.
TMPH-00102	RBP47A Protein, Arabidopsis thaliana, Recombinant (His & Myc)	Arabidopsis thaliana	E. coli
	Heterogeneous nuclear ribonucleoprotein (hnRNP)-protein binding the poly(A) tail of mRNA and probably involved in some steps of pre-mRNA maturation. RBP47A Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.5 kDa and the accession number is F4I3B3.
TMPH-02055	RBPMS Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA. RBPMS Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-...
TMPY-03983	CIRBP Protein, Human, Recombinant (His) cold inducible RNA binding protein,CIRP	Human	E. coli
	CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator.CIRBP can bind the 3 translated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for...
TMPH-02587	CIRBP Protein, Mouse, Recombinant (His) CIRP,A18 hnRNP,Glycine-rich RNA-binding protein CIRP,CIR...	Mouse	E. coli
	Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Promotes assembly of stress granules (SGs), when overexpressed. Seems to play an essential role in cold-induced suppression of cell proliferation. Acts as a translational repressor. Acts as a translational activator. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN.
TMPH-01110	CIRBP Protein, Human, Recombinant (GST) A18HNRNP,CIRP,Glycine-rich RNA-binding protein CIRP,A18 hnRN...	Human	E. coli
	CIRBP Protein, Human, Recombinant (GST) is expressed in E. coli.

重组蛋白

RBP4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01567

Species: Mouse

Expression System: HEK293 Cells

RBP4 Protein, Human, Recombinant

Cat.No: TMPJ-00084

Species: Human

Expression System: E. coli

RBP5 Protein, Human, Recombinant

Cat.No: TMPJ-01063

Species: Human

Expression System: E. coli

RBP5 Protein, Human, Recombinant (His)

Cat.No: TMPY-04076

Species: Human

Expression System: E. coli

RBP2 Protein, Human, Recombinant

Cat.No: TMPJ-00992

Species: Human

Expression System: E. coli

RBP4 Protein, Human, Recombinant (His)

Cat.No: TMPY-00907

Species: Human

Expression System: HEK293 Cells

RBP3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00829

Species: Human

Expression System: E. coli

RBP1 Protein, Human, Recombinant

Cat.No: TMPJ-00814

Species: Human

Expression System: E. coli

CRABP2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01549

Species: Human

Expression System: E. coli

CRABP1 Protein, Human, Recombinant

Cat.No: TMPY-03864

Species: Human

Expression System: E. coli

RBP7 Protein, Human, Recombinant (His)

Cat.No: TMPY-04056

Species: Human

Expression System: E. coli

RBP4 Protein, Canine, Recombinant (His)

Cat.No: TMPY-02861

Species: Canine

Expression System: HEK293 Cells

RBP4 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-03591

Species: Cynomolgus

Expression System: HEK293 Cells

RBP4 Protein, Canine, Recombinant (hFc)

Cat.No: TMPY-02834

Species: Canine

Expression System: HEK293 Cells

RBP4 Protein, Rat, Recombinant (His)

Cat.No: TMPY-01611

Species: Rat

Expression System: HEK293 Cells

RBP47A Protein, Arabidopsis thaliana, Recombinant (His & Myc)

Cat.No: TMPH-00102

Species: Arabidopsis thaliana

Expression System: E. coli

RBPMS Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02055

Species: Human

Expression System: E. coli

CIRBP Protein, Human, Recombinant (His)

Cat.No: TMPY-03983

Species: Human

Expression System: E. coli

CIRBP Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02587

Species: Mouse

Expression System: E. coli

CIRBP Protein, Human, Recombinant (GST)

Cat.No: TMPH-01110

Species: Human

Expression System: E. coli

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