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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T62106 |
(Rac)-ErSO-DFP
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(Rac)-ErSO-DFP 是一种 ErSO-DFP 的衍生物,也是一种选择性小分子 Erα 生物调节剂。(Rac)-ErSO-DFP 能够过度激活 ERα+ 依赖性的预期未折叠蛋白反应,表现出抗雌激素受体 α 阳性乳腺癌 (包括其抗性肿瘤) 的作用。 | |||
T62108 | ErSO-DFP | ||
ErSO-DFP 是一种预期的未折叠蛋白反应 (a-UPR) 激活剂。ErSO-DFP 能够提高对雌激素受体α+ (ERα+) 癌细胞的选择性,选择性高于 ErSO。ErSO-DFP 具有抗肿瘤作用,能够明显消除小鼠模型中 MCF-7 肿瘤。 | |||
T13863 |
(rel)-Myrislignan
|
Others | Others |
(rel)-Myrislignan, a lignan compound with a relative configuration, has been isolated from Myristica fragrans Houtt. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1165 |
(Rac)-Myrislignan
1-(3,4-dimethoxyphenyl)-2-(4-allly-2,6-dimethoxyphenoxy)propan-1-ol,rac-myrislignan,ALPHA-[1-[2,6-二甲氧基-4-(2-丙烯-1-基)苯氧基]乙基]-4-羟 |
Others | Others |
1-(3,4-Dimethoxyphenyl)-2-(4-allly-2,6-dimethoxyphenoxy)propan-1-ol shows anti-staphylococcal activity against a total of five multidrug-resistant (MDR) and methicillin-resistant Staphylococcus aureus strains and the minimum inhibitory concentrations (MIC | |||
T4S1540 |
Myrislignan
|
Apoptosis; NF-κB | Apoptosis; NF-κB |
Myrislignan 是一种木酚素,从Myristica fragransHoutt 分离得到,具有抗炎作用。它通过抑制NF-kB 信号通路的激活,减轻LPS 诱导的小鼠巨噬细胞炎症反应。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04552 |
AKT1 Protein, Human, Recombinant (His)
RAC-ALPHA,v-akt murine thymoma viral oncog... |
Human | Baculovirus Insect Cells |
v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to insulin, insulin-like growth factor 1 (IGF1), and glucose. AKT1 also plays a key role in the regulation of both muscle cell hypertrophy and atrophy. AKT1 activity is required for physiologic cardiac growth in response to IGF1 stimulation or exercise training. In contrast, AKT1 ac... |