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Search Results for " pyrazinamide "

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T10171 5-Hydroxypyrazine-2-Carboxylic Acid

Others Others
5-Hydroxypyrazine-2-Carboxylic Acid is a metabolite of anti-tuberculosis drug pyrazinamide.
T37880 OPC-167832

OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-167832 exhibits very low MICs against laboratory strains of M. tuberculosis H37Rv (MIC: 0.0005 μg/ml) and Kurono (MIC: 0.0005 μg/ml) and strains with monoresistance to rifampin (RIF), isoniazid (INH), ethambutol (EMB), streptomycin (STR), and pyrazinamide (PZA) (MIC: 0.00024-0.001 ...

化合物

5-Hydroxypyrazine-2-Carboxylic Acid
Cat.No: T10171
Synonym:
Target: Others
OPC-167832
Cat.No: T37880
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T1426 Pyrazinamide

Pyrazinoic acid amide,Pyrazinecarboxamide,吡嗪酰胺

Antibacterial; Antibiotic; Autophagy; Fatty Acid Synthase Autophagy; Metabolism; Microbiology/Virology
Pyrazinamide (Pyrazinecarboxamide) 是一种口服抗结核类抗生素。它是一种前药,通过结核分枝杆菌pncA 基因编码的 PZase/烟酰胺酶转化为活性吡嗪酸形式。

天然产物

Pyrazinamide
Cat.No: T1426
Synonym: Pyrazinoic acid amide,Pyrazinecarboxamide,吡嗪酰胺
Target: Antibacterial, Antibiotic, Autophagy, Fatty Acid Synthase
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