Cat. No. | Product Name | Target | Signaling Pathways |
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T15389L |
Glucagon (1-29), bovine, human, porcine hydrochloride
盐酸胰高血糖素,Porcine glucagon hydrochloride,Glucagon hydrochloride |
Glucocorticoid Receptor; Glucagon Receptor | Endocrinology/Hormones; GPCR/G Protein |
Glucagon (1-29), bovine, human, porcine hydrochloride 是一种由胰腺 α 细胞产生的多肽激素。它可激活 HNF4α 并促进 HNF4α 磷酸化,促进糖异生。 | |||
T15389 |
Glucagon (1-29), bovine, human, porcine
胰高血糖素,Porcine glucagon,Glucagon |
Others | Others |
Glucagon is a peptide hormone, produced by pancreatic α-cells. Glucagon reduces the activity of HNF-4. Glucagon stimulates gluconeogenesis. Glucagon enhances HNF4α phosphorylation. | |||
T80030 |
Oxyntomodulin (bovine, porcine) (TFA)
Glucagon-37 (bovine, porcine) (TFA) |
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Oxyntomodulin (bovine, porcine) TFA为含37个氨基酸的肽类激素,作为胰高血糖素样肽1 (GLP-1) 受体的激动剂。 | |||
T76332 |
Biotinyl-Glucagon (1-29), human, bovine, porcine
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Biotinyl-Glucagon (1-29), human, bovine, porcine 为带生物素标记的Glucagon衍生物,此肽类激素由胰腺α细胞分泌,功能是提升血液中的葡萄糖与脂肪酸浓度。 | |||
T83550 |
(Asp28)-Glucagon (1-29) (human, rat, porcine)
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'(Asp28)-Glucagon (1-29) (human, rat, porcine)' 为胰高血糖素的一种改良型结构,在第28位氨基酸残基上天冬氨酸(Asp)替换原有残基,显著提高了该化合物在生理pH条件下的溶解性,且保持了与天然胰高血糖素相同的生物活性。 | |||
T76628 |
(Met(O)27)-Glucagon (1-29) (human, rat, porcine)
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'(Met(O)27)-Glucagon (1-29) (human, rat, porcine) 为修饰版胰高血糖素。在大鼠肝细胞内,其促进葡萄糖合成的活性虽与天然胰高血糖素相似,但呈现出较低效率,暗示蛋氨酸对于胰高血糖素与其肝脏受体绑定具有关键性作用。' | |||
T35627 |
Amylin (human) (trifluoroacetate salt)
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Amylin is a 37-residue peptide hormone secreted from pancreatic β-cells that reduces food intake, decreases glucagon secretion, slows gastric emptying, and increases satiety. It binds to amylin receptors with IC50 values of 2 and 0.2 nM for porcine and guinea pig nucleus accumbens membrane preparations, respectively. Amylin is present in amyloid aggregates derived from the pancreatic islets of humans with type 2 diabetes. Amylin forms fibrils that react to thioflavin T and are organized in a cro... |