Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP2401 |
Peptide T amide
D-Ala(1)-peptide T amide |
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Peptide T amide is an octapeptide segment of HIV envelope gp120 and is used in AIDS therapy. | |||
T7624 |
DAPTA
DAPTA(TFA),D-Ala-peptide T-amide,Adaptavir |
HIV Protease; CCR | Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome |
DAPTA (Adaptavir) 是一种合成肽,是 CCR5抑制剂,有抗 HIV 的活性。 | |||
T35955 |
PAR2 (1-6) amide (human) (trifluoroacetate salt)
PAR2 (1-6) amide (human) (trifluoroacetate salt) |
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PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-length sequence.1It binds to NCTC 2544 cells expressing human PAR2 (Ki= 9.64 μM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50= 0.075 μM).2PAR2 (1-6) amide (100 μM) reduces colony formation of A549 lung cancer cells.1It induces superoxide prod... | |||
T37522 | Teneligliptin | ||
Teneligliptin (MP-513) is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM. Teneligliptin (MP-513) inhibits all these DPP-4 enzymes in a concentration-dependent manner. The IC50s of Teneligliptin (MP-513) for rhDPP-4, human plasma, and rat plasma are 0.889, 1.75, and 1.35 nM, respectively. A study of enzyme inhibition kinetics is conducted for Teneligliptin (M... |