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Search Results for " ptl "

1

抑制剂 & 化合物

1

天然产物

25

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T31550	DMA-CPPTL DMACPPTL,DMA CPPTL
	DMA-CPPTL is a prodrug of CPPTL which induces apoptosis in a dose-dependent manner via the ROS/JNK pathway in acute myeloid leukemia.

化合物

Cat.No: T31550

Synonym: DMACPPTL,DMA CPPTL

Cat. No.	Product Name	Target	Signaling Pathways
T11060	DMAPT Dimethylamino Parthenolide	NF-κB	NF-κB
	DMAPT (Dimethylamino Parthenolide) 是一种具有口服活性的NF-κB 抑制剂，是一种 Parthenolide (PTL) 的类似物，对原发性急性髓性白血病细胞的LD50值为1.7 μM。具有潜在的抗肿瘤和抗转移作用。

天然产物

Cat.No: T11060

Synonym: Dimethylamino Parthenolide

Target: NF-κB

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03222	PNLIP Protein, Human, Recombinant (His) PL,pancreatic lipase,PTL,PNLIPD	Human	HEK293 Cells
	PNLIP is an enzyme that belongs to the lipase family. Secreted from the pancreas, PNLIP is the primary lipase that hydrolyzes dietary fat molecules in the human digestive system, converting triglyceride substrates found in ingested oils to monoglycerides and free fatty acids. Bile salts secreted from the liver and stored in gallbladder are released into the duodenum where they coat and emulsify large fat droplets into smaller droplets, thus increasing the overall surface area of the fat, which a...
TMPY-03523	ANGPTL4 Protein, Human, Recombinant (His) NL2,HFARP,angiopoietin-like 4,ARP4,PGAR,FIAF,TGQTL,ANGPT...	Human	HEK293 Cells
	ANGPTL4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.5 kDa and the accession number is Q9BY76.
TMPY-05053	ANGPTL2 Protein, Human, Recombinant (His) HARP,angiopoietin-like 2,ARP2	Human	HEK293 Cells
	ANGPTL2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.4 kDa and the accession number is A0A024R868.
TMPK-00299	ANGPTL2 Protein, Human, Recombinant (His & Avi), Biotinylated MGC8889,ANGRP2,angiopoietin-like 2,ANGPTL2,HARP,ARP...	Human	HEK293 Cells
	Angiopoietin-like 2 (ANGPTL2) is a proinflammatory protein belonging to the angiopoietin-like family. ANGPTL2 is secreted and detected in the systemic circulation. Different observational clinical studies reported that circulating levels of ANGPTL2 increase significantly in various chronic inflammatory diseases and showed associations between ANGPTL2 levels and diagnosis and/or prognosis of cardiovascular diseases, diabetes, chronic kidney disease, and various types of cancers. ANGPTL2 Protein, ...
TMPK-00285	ANGPTL3 Protein, Human, Recombinant (His & Avi), Biotinylated ANGPTL3,FHBL2,ANGPT5,Angiopoietin-5,ANL3,ANG-5,Angi...	Human	HEK293 Cells
	ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake. ANGPTL3...
TMPJ-01196	ANGPTL8 Protein, Human, Recombinant (hFc) βtrophin,Angiopoietin-like protein 8,Lipasin,Angptl...	Human	HEK293 Cells
	The protein specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. It promotes pancreatic beta cell proliferation without insulin resistance. Also it acts as a blood lipid regulator by regulating serum triglyceride levels and possibly by promoting ANGPTL3 cleavage. It interacts with ANGPTL3. It predominantly expressed in liver and also expressed in adipose tissues. The ability of the protein to induce pancreatic beta cell proli...
TMPY-01217	ANGPTL5 Protein, Human, Recombinant (GST) angiopoietin like 5,ANGPTL5	Human	Baculovirus Insect Cells
	The angiopoietins are protein growth factors that promote angiogenesis, the formation of blood vessels from pre-existing blood vessels. There are now four identified angiopoietins: Ang1, Ang2, Ang3, Ang4. In addition, there are a number of proteins that are closely related to angiopoietins (ANGPTL2, ANGPTL3, ANGPTL4, ANGPTL5, ANGPTL6, ANGPTL7). Angiopoietin-like 5 (ANGPTL5) is mainly expressed in adult heart. Like other members of the angiopoietin family, ANGPTL5-deduced protein also has an N-te...
TMPK-00730	ANGPTL7 Protein, Human, Recombinant (His & Avi) Angiopoietin-like factor,angiopoietin-like 7,AngX,ANGPTL...	Human	HEK293 Cells
	ANGPTL7 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 40.2 kDa and the accession number is O43827.
TMPJ-00286	ANGPTL3 Protein, Human, Recombinant (hFc) ANGPTL3,ANGPT5,Angiopoietin-related protein 3,ANG-5...	Human	HEK293 Cells
	Angiopoietin-like 3 (ANGPTL3) is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Full length ANGPTL3 circulates in the plasma as do the proteolytically separated N-and C-terminal segments containing the coiled coil domain and fibrinogen-like domains,respectively. ANGPTL3 directly inhibits ...
TMPH-02509	ANGPTL8 Protein, Mouse, Recombinant (E. coli, His) Angiopoietin-like protein 8,Lipasin,Gm6484,Refeeding-induced...	Mouse	E. coli
	Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state. According to a report, may act by promoting ANGPTL3 cleavage. According to another study, not required for cleavage of ANGPTL3.
TMPY-04084	ANGPTL1 Protein, Canine, Recombinant (hFc) angiopoietin-like 1	Canine	HEK293 Cells
	Angiopoietin-like protein 1 (ANGPTL1) has been reported to suppress migration and invasion in lung and breast cancer, acting as a novel tumor suppressor candidate. Downregulation of tumor suppressor signaling plays an important role in the pathogenesis of hepatocellular carcinoma (HCC).The downregulation of the angiopoietin-like protein ANGPTL1 is associated with vascular invasion, tumor thrombus, metastasis, and poor prognosis in HCC. Ectopic expression of ANGPTL1 in HCC cells effectively decre...
TMPK-01329	ANGPTL4 Protein, Cynomolgus, Recombinant (His) PGAR,AGP4,NGPTL2,ANG4,ANGPTL4,pp1158,HFARP...	Cynomolgus	HEK293 Cells
	Candidates for this common regulatory system include signals mediated by peroxisome proliferator-activated regulator and its response factor, angiopoietin-like 4. The expression and bioactivity of angiopoietin-like 4, an adipocytokine that was originally reported to have an angiogenic function, have been detected not only in the vascular system and adipose tissue but also in rheumatoid joints.
TMPH-02079	SPTLC2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate. Plays an important role in de novo sphyngolipid biosynthesis which is crucial for adipogenesis. SPTLC2 Protein, Human, Recomb...
TMPY-05286	ANGPTL3 Protein, Human, Recombinant (His) FHBL2,ANL3,ANGPT5,angiopoietin-like 3,ANG-5	Human	Baculovirus Insect Cells
	ANGPTL3 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 53.3 kDa and the accession number is Q9Y5C1.
TMPJ-00680	ANGPTL7 Protein, Human, Recombinant (His) CDT6,Cornea-derived transcript 6 protein,Angiopoietin-like p...	Human	HEK293 Cells
	Angiopoietin-like 7 (ANGPTL7) is a secreted glycoprotein that is structurally related to the angiopoietins. Members of this protein family contain an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL7 shares 89% aa sequence identity with mouse and rat ANGPTL7. It is secreted as a 45-50kDa monomer that forms disulfide-linked homotrimers and tetramers via the coiled coil domain. ANGPTL7 is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated ...
TMPY-02878	ANGPTL4 Protein, Human, Recombinant (hFc) TGQTL,angiopoietin-like 4,pp1158,PGAR,ANGPTL2,NL2,A...	Human	HEK293 Cells
	ANGPTL4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 55.5 kDa and the accession number is Q9BY76.
TMPY-04030	ANGPTL4 Protein, Mouse, Recombinant (His) Bk89,Pgarg,Pgar,Ng27,Arp4,Pp1158,Hfarp,Fiaf,angiopoietin-lik...	Mouse	HEK293 Cells
	ANGPTL4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.9 kDa and the accession number is Q9Z1P8.
TMPY-05451	ANGPTL3 Protein, Cynomolgus, Recombinant (His) angiopoietin-like 3	Cynomolgus	Baculovirus Insect Cells
	ANGPTL3 Protein, Cynomolgus, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 25.2 kDa and the accession number is A0A2K5UDC5.
TMPK-00284	ANGPTL3 Protein, Human, Recombinant (His & Avi) FHBL2,Angiopoietin-like Protein 3,ANG-5,ANGPTL3,ANG...	Human	HEK293 Cells
	ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake. ANGPTL3...
TMPK-00731	ANGPTL7 Protein, Human, Recombinant (hFc) angiopoietin-like 7,Angiopoietin-like factor,ANGPTL...	Human	HEK293 Cells
	ANGPTL7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 63.8 kDa and the accession number is O43827.
TMPK-00298	ANGPTL2 Protein, Human, Recombinant (His & Avi) ANGRP2,ANGPTL2,angiopoietin-like 2,HARP,MGC8889,ARP...	Human	HEK293 Cells
	Angiopoietin-like 2 (ANGPTL2) is a proinflammatory protein belonging to the angiopoietin-like family. ANGPTL2 is secreted and detected in the systemic circulation. Different observational clinical studies reported that circulating levels of ANGPTL2 increase significantly in various chronic inflammatory diseases and showed associations between ANGPTL2 levels and diagnosis and/or prognosis of cardiovascular diseases, diabetes, chronic kidney disease, and various types of cancers. ANGPTL2 Protein, ...
TMPH-02510	ANGPTL8 Protein, Mouse, Recombinant (His) Rifl,Refeeding-induced fat and liver protein,Betatrophin,Ang...	Mouse	P. pastoris (Yeast)
	Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state. According to a report, may act by promoting ANGPTL3 cleavage. According to another study, not required for cleavage of ANGPTL3. ANGPTL8 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 22.5 kDa and the...
TMPY-03998	ANGPTL2 Protein, Mouse, Recombinant (hFc) Arp2,AI593246,AW260363,angiopoietin-like 2	Mouse	HEK293 Cells
	ANGPTL2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.5 kDa and the accession number is Q9R045.
TMPY-05294	ANGPTL3 Protein, Mouse, Recombinant (His) angiopoietin-like 3,hypl	Mouse	Baculovirus Insect Cells
	ANGPTL3 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 52.2 kDa and the accession number is Q3UEF5.
TMPJ-01415	ANGPTL4 Protein, Mouse, Recombinant (hFc) Angptl4,HFARP,Fasting-induced adipose factor,Fiaf,S...	Mouse	HEK293 Cells
	Angiopoietin-related protein 4（ANGPTL4）is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity...

重组蛋白

PNLIP Protein, Human, Recombinant (His)

Cat.No: TMPY-03222

Species: Human

Expression System: HEK293 Cells

ANGPTL4 Protein, Human, Recombinant (His)

Cat.No: TMPY-03523

Species: Human

Expression System: HEK293 Cells

ANGPTL2 Protein, Human, Recombinant (His)

Cat.No: TMPY-05053

Species: Human

Expression System: HEK293 Cells

ANGPTL2 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00299

Species: Human

Expression System: HEK293 Cells

ANGPTL3 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00285

Species: Human

Expression System: HEK293 Cells

ANGPTL8 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-01196

Species: Human

Expression System: HEK293 Cells

ANGPTL5 Protein, Human, Recombinant (GST)

Cat.No: TMPY-01217

Species: Human

Expression System: Baculovirus Insect Cells

ANGPTL7 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00730

Species: Human

Expression System: HEK293 Cells

ANGPTL3 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00286

Species: Human

Expression System: HEK293 Cells

ANGPTL8 Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02509

Species: Mouse

Expression System: E. coli

ANGPTL1 Protein, Canine, Recombinant (hFc)

Cat.No: TMPY-04084

Species: Canine

Expression System: HEK293 Cells

ANGPTL4 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01329

Species: Cynomolgus

Expression System: HEK293 Cells

SPTLC2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02079

Species: Human

Expression System: E. coli

ANGPTL3 Protein, Human, Recombinant (His)

Cat.No: TMPY-05286

Species: Human

Expression System: Baculovirus Insect Cells

ANGPTL7 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00680

Species: Human

Expression System: HEK293 Cells

ANGPTL4 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02878

Species: Human

Expression System: HEK293 Cells

ANGPTL4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04030

Species: Mouse

Expression System: HEK293 Cells

ANGPTL3 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-05451

Species: Cynomolgus

Expression System: Baculovirus Insect Cells

ANGPTL3 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00284

Species: Human

Expression System: HEK293 Cells

ANGPTL7 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00731

Species: Human

Expression System: HEK293 Cells

ANGPTL2 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00298

Species: Human

Expression System: HEK293 Cells

ANGPTL8 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02510

Species: Mouse

Expression System: P. pastoris (Yeast)

ANGPTL2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03998

Species: Mouse

Expression System: HEK293 Cells

ANGPTL3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05294

Species: Mouse

Expression System: Baculovirus Insect Cells

ANGPTL4 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-01415

Species: Mouse

Expression System: HEK293 Cells

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