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Cat. No.	Product Name	Target	Signaling Pathways
T18632	PROTAC MDM2 Degrader-2	Others	Others
	PROTAC MDM2 Degrader-2 is a compound designed utilizing PROTAC technology, functioning as a MDM2 degrader. Comprised of a highly potent inhibitor targeting MDM2, a linker, and the MDM2 ligand for E3 ubiquitin ligase, this compound facilitates the degradation of MDM2[1].
T18633	PROTAC MDM2 Degrader-3	Others	Others
	PROTAC MDM2 Degrader-3 is a compound that leverages PROTAC technology to degrade MDM2. It consists of a highly effective MDM2 inhibitor, a linker, and the MDM2 ligand for E3 ubiquitin ligase[1].
T18631	PROTAC MDM2 Degrader-1	Others	Others
	PROTAC MDM2 Degrader-1 is a chemical compound that utilizes PROTAC technology to degrade MDM2. This compound is comprised of a highly effective MDM2 inhibitor, a linker, and the MDM2 ligand for E3 ubiquitin ligase[1].
T18634	PROTAC MDM2 Degrader-4	Others	Others
	PROTAC MDM2 Degrader-4 is a compound designed using PROTAC technology to degrade MDM2. It combines a powerful MDM2 inhibitor, a linker, and the MDM2 ligand for E3 ubiquitin ligase[1].
T37041	MD-222
	MD-222, a pioneering, highly potent PROTAC degrader targeting MDM2, efficiently mediates the rapid degradation of MDM2 protein and activates wild-type p53 within cells, showcasing significant anticancer effects[1][2].
T18609	PROTAC ERRα Degrader-2	Others	Others
	PROTAC ERRα Degrader-2 is a compound consisting of an MDM2 ligand binding group, a linker, and an estrogen-related receptor alpha (ERRα) binding group. This compound is designed to specifically degrade estrogen-related receptor alpha (ERRα), acting as an ERRα degrader[1].
T18055	K-Ras ligand-Linker Conjugate 2	Others	Others
	K-Ras ligand-Linker Conjugate 2 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker. This compound is capable of recruiting E3 ligases like VHL, CRBN, MDM2, and IAP. It is utilized in the synthesis of PROTAC K-Ras Degrader-1, which is a highly effective PROTAC K-Ras degrader with a degradation efficacy of ≥70% in SW1573 cells[1].

化合物

PROTAC MDM2 Degrader-2

Cat.No: T18632

Target: Others

PROTAC MDM2 Degrader-3

Cat.No: T18633

Target: Others

PROTAC MDM2 Degrader-1

Cat.No: T18631

Target: Others

PROTAC MDM2 Degrader-4

Cat.No: T18634

Target: Others

Cat.No: T37041

PROTAC ERRα Degrader-2

Cat.No: T18609

Target: Others

K-Ras ligand-Linker Conjugate 2

Cat.No: T18055

Target: Others

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