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Cat. No.	Product Name	Target	Signaling Pathways
T18629	PEG3-O-CH2COOH PROTAC Linker 8,三聚乙二醇-乙酸	Others; PROTAC Linker	Others; PROTAC
	PEG3-O-CH2COOH (PROTAC Linker 8) 是一种属于 PEG 类的 PROTAC linker，可用于 SNIPER 分子的合成。
T15304	Fmoc-8-amino-3,6-dioxaoctanoic acid Fmoc-NH-PEG2-CH2COOH,[2-[2-(Fmoc-氨基)乙氧基]乙氧基]乙酸	PROTAC Linker	PROTAC
	Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) 是一种可裂解的 ADC 连接剂，用于合成抗体-药物偶联物。它也是一种基于 PEG 的 PROTAC 接头，可用于 PROTAC 的合成。
T17909	(S,R,S)-AHPC-PEG3-N3 VHL Ligand-Linker Conjugates 8,VH032-PEG3-N3,E3 ligase Ligand-Linker Conjugates 12	Others; E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase	Others; PROTAC
	(S,R,S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) 包含基于 (S,R,S)-AHPC 的 VHL 配体和 3 个单元 PEG linker，是一种合成的 E3 连接酶配体-linker 偶联物。
T17879	E3 ligase Ligand 8	Others; Ligand for E3 Ligase	Others; PROTAC
	E3 ligase Ligand 8 是 E3 泛素连接酶配体。它能够利用 linker 与靶蛋白配体连接，形成 PROTAC 分子。PROTAC 可诱导促癌蛋白发生泛素化降解。
T40148	Pom-8PEG
	Pom-8PEG is an E3 ubiquitin ligase ligand-linker conjugate consisting of a cereblon (CRBN) ligand and an 8-unit PEG linker. This compound can be utilized for the synthesis of PROTAC, including the IDO1 PROTAC degrader.
T17900	cIAP1 Ligand-Linker Conjugates 8 E3 ligase Ligand-Linker Conjugates 46	Others	Others
	cIAP1 Ligand-Linker Conjugates 8 comprises an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is specifically utilized for the purpose of SNIPER design[1].
T40149	Thalidomide-NH-PEG8-Ts Thalidomide-NH-PEG8-Ts
	Thalidomide-NH-PEG8-Ts is a chemically synthesized conjugate consisting of a Thalidomide-based cereblon ligand and an 8-unit PEG linker. This conjugate serves as an E3 ligase ligand-linker in PROTAC technology applications, including the degradation of IDO1 by a PROTAC degrader.
T14479	Azido-PEG8-NHS ester	Others	Others
	Azido-PEG8-NHS ester is an 8 unit PEG linker with cleavable properties, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1]. This compound also serves as a PEG- and Alkyl/ether-based PROTAC linker, enabling its utilization in the synthesis of PROTACs[2].
T71872	Boc-8-aoc-oh
	Boc-8-aoc-oh can be used as a PROTAC linker in the synthesis of PROTACs. Boc-8-aoc-oh is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
T71972	N-Fmoc-8-aminooctanoic acid
	N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.