Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15191 |
PROTAC ERRα ligand 1
|
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
PROTAC ERRα ligand 1 是一种雌激素相关受体 α (ERRα) 拮抗剂,能够作用于 ERRα (IC50:0.04 μM)和 ERRγ (IC50:2.8 μM)。 | |||
T17941 |
ERRα Ligand-Linker Conjugates 1
|
Others | Others |
ERRα Ligand-Linker Conjugates 1 refers to a chemical compound that consists of a ligand targeting estrogen-related receptor alpha (ERRα), and a PROTAC linker that facilitates the recruitment of E3 ligases MDM2. It finds utility in the synthesis of a range of PROTACs, including one known as PROTAC ERRalpha Degrader-1. With its capability to induce degradation of ERRα, PROTAC ERRalpha Degrader-1 functions as an ERRα degrader[1]. |