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Cat. No.	Product Name	Target	Signaling Pathways
TP2141L	Balixafortide POL6326	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	Balixafortide (POL6326) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM and it is also a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. Anti-cancer effects[1][2]. Balixafortide blocks β-arresti
TP2141	Balixafortide TFA (1051366-32-5 free base) Balixafortide TFA,POL6326 TFA	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	Balixafortide TFA (POL6326 TFA) is a selective, well-tolerated peptidic CXCR4 antagonist (IC50 < 10 nM). It shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7. Balixafortide TFA blocks β-arrestin recruitment and calcium fl
T75999	Balixafortide TFA
	Balixafortide TFA (POL6326 TFA) 是一种有效的，选择性的，耐受性好的肽类CXCR4拮抗剂，其IC50小于 10 nM。Balixafortide TFA 对CXCR4的选择性比包括CXCR7在内的许多受体高出 1000 倍。Balixafortide TFA 以 IC50< 10 nM 阻断β-arrestin 募集和钙通量。Balixafortide TFA 还是一种有效的造血干细胞和祖细胞 (HSPC) 动员剂，并具有抗癌作用。