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Search Results for " pn2 "

Targets Recommended: Phosphatase

4

抑制剂 & 化合物

6

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T79160	PROTAC PTPN2 degrader-2	Phosphatase	Metabolism
	PROTACPTPN2 degrader-2（example 187B）作为PTPN2降解剂，展现出对研究癌症和代谢性疾病的有效性。
T40216	PTPN22-IN-1 PTPN22-IN-1
	PTPN22-IN-1 is a potent PTPN22 inhibitor ( IC 50 =1.4 μM; K i =0.50 μM). PTPN22-IN-1 exhibits >7-10 fold selectivity for PTPN22 over similar phosphatases. PTPN22-IN-1 augments antitumor immune responses. From WO2021007491A1 compound L-1.
T74732	PROTAC PTPN2 degrader-1
	PROTACPTPN2 degrader-1 (compound example 77) 是一种有效的 PTPN2降解剂。PROTACPTPN2 degrader-1 具有研究癌症或代谢性疾病的潜力。
T79161	PROTAC PTPN2 degrader-2 TFA	Phosphatase	Metabolism
	PROTACPTPN2 degrader-2（例187B）TFA 作为PTPN2降解剂，展现出对癌症及代谢性疾病研究的潜在效用。

化合物

PROTAC PTPN2 degrader-2

Cat.No: T79160

Target: Phosphatase

Cat.No: T40216

Synonym: PTPN22-IN-1

PROTAC PTPN2 degrader-1

Cat.No: T74732

PROTAC PTPN2 degrader-2 TFA

Cat.No: T79161

Target: Phosphatase

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00668	APP/Protease nexin-II Protein, Human, Recombinant (hFc) CTFγ,amyloid beta (A4) precursor protein,AAA,ABPP,CVAP,APPI,...	Human	HEK293 Cells
	APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8.
TMPY-03884	Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST) CTFgamma,PN-II,AAA,Aβ,PN2,APPI,AD...	Human	E. coli
	Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.2 kDa and the accession number is P05067-1.
TMPY-02221	Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST) CVAP,PN2,amyloid β (A4) precursor protein,...	Human	E. coli
	Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.4 kDa and the accession number is P05067-1.
TMPY-03885	Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) AD1,AAA,ABETA,CVAP,PN-II,CTFgamma,Aβ,APPI,PN	Human	E. coli
	Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.1 kDa and the accession number is P05067-1.
TMPY-02110	Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) AD1,ABPP,CTFγ,APPI,ABETA,β-amyloid 40/β-APP40,Aβ,CVAP,CTFgam...	Human	E. coli
	Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 31.8 kDa and the accession number is P05067-1.
TMPH-01031	CAPN2 Protein, Human, Recombinant (His) Calpain-2 catalytic subunit,Millimolar-calpain,Calp...	Human	E. coli
	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs. CAPN2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 82...

重组蛋白

APP/Protease nexin-II Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00668

Species: Human

Expression System: HEK293 Cells

Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST)

Cat.No: TMPY-03884

Species: Human

Expression System: E. coli

Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02221

Species: Human

Expression System: E. coli

Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST)

Cat.No: TMPY-03885

Species: Human

Expression System: E. coli

Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02110

Species: Human

Expression System: E. coli

CAPN2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01031

Species: Human

Expression System: E. coli

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