Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6945 |
Vps34-PIK-III
PIK-III,VPS34-IN2 |
PI3K; Autophagy | Autophagy; PI3K/Akt/mTOR signaling |
Vps34-PIK-III (VPS34-IN2) 是 VPS34 酶活性的选择性抑制剂,IC50值为18 nM。它可抑制自噬并导致自噬底物稳定。 | |||
T7944 |
VPS34 inhibitor 1 (Compound 19, PIK-III analogue)
PIK-III analogue |
PI3K | PI3K/Akt/mTOR signaling |
VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) 是一种有效的选择性 VPS34抑制剂( IC50 : 15 nM)。 |