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Cat. No. Product Name Target Signaling Pathways
T62409 PI3K-IN-23

PI3K-IN-23 是一种 (E)-9-oxooctadec-10-en-12-ynoic acid 类似物,能够促进葡萄糖摄取 (EC50: 7.00 μM)。
T2365 Pilaralisib

SAR245408,XL-147

PI3K PI3K/Akt/mTOR signaling
Pilaralisib (XL-147) 是一种有效的、选择性的 I 类PI3Ks 抑制剂,能够抑制 PI3Kα (IC50:39 nM),PI3Kβ (IC50:383 nM),PI3Kγ (IC50:23 nM) 和 PI3Kδ (IC50:36 nM)。
T28862 ST-168

ST168,ST 168

ST-168 is a potent inhibitor of PI3K and MEK. ST-168 displays improved PI3K and MEK1 isoform inhibition. ST-168 demonstrated a 2.8-, 2.7-, 23-, and 2.5-fold improved inhibition toward the PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ isoforms and a 2.2-fold improvement
T68485 Apilimod HCl

Apilimod dimesylate is a potent and selective PIKfyve inhibitor. It exhibits no significant activity at other lipid kinases and protein kinases, including PIP4K, PIP5K, mTOR, PI3K and PI4K. Apilimod dimesylate inhibits cellular entry by SARS-CoV-2, MERS-CoV and MHV S pseudovirions. It reduces the number of SARS-CoV-2-infected hiPSC-derived pneumocyte-like cells by 85% and inhibits SARS-CoV-2 replication in donor lung tissue. It also exhibits selective cytotoxicity in B-cell non-Hodgkin lymphoma ...

化合物

PI3K-IN-23
Cat.No: T62409
Synonym:
Target:
Pilaralisib
Cat.No: T2365
Synonym: SAR245408,XL-147
Target: PI3K
ST-168
Cat.No: T28862
Synonym: ST168,ST 168
Target:
Apilimod HCl
Cat.No: T68485
Synonym:
Target:
TargetMol Loading
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