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Cat. No. Product Name Target Signaling Pathways
T81467 PI3Kδ-IN-18

PI3K PI3K/Akt/mTOR signaling
Se15作为PI3Kδ选择性抑制剂展现出高度效力,具有小于0.1nM的IC50值,主要应用于自身免疫反应研究领域。
T36308 PF-06843195

PF-06843195 is a highly selective PI3Kα inhibitor with an IC50 of 18 nM in Rat1 fibroblasts. The Kis of PF-06843195 for PI3Kα and PI3Kδ in biochemical kinase assay are less than 0.018 nM and 0.28 nM, respectively. PF-06843195 has great suppression of the PI3K/mTOR signaling pathway and durable antitumor efficacy[1]. PF-06843195 inhibits the breast cancer cell lines MCF7 and T47D proliferation with IC50s of 62 nM and 32 nM, respectively[1].PF-06843195 inhibits pAKT (T308) in MCF7 and T47D cells w...

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PI3Kδ-IN-18
Cat.No: T81467
Synonym:
Target: PI3K
PF-06843195
Cat.No: T36308
Synonym:
Target:
TargetMol Loading
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