Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1953 |
PG-931
PG 931 |
||
Potent and selective melanocortin 4 (MC4) receptor agonist (IC50 values are 0.58 and 55 nM for human MC4 and MC3 receptors respectively). Produces a rapid and dose dependent restoration of cardiovascular and respiratory function in hemorrhage-shocked rats | |||
TP1953L |
PG 931 acetate
PG 931 acetate (667430-81-1 Free base) |
Melanin-concentrating Hormone Receptor (MCHR) | GPCR/G Protein |
PG 931 acetate 是一种强效的黑素皮质素4(MC4)受体的激动剂。 | |||
T75847 |
PG-931 TFA
|
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PG-931 TFA 是 SHU 9119 的类似物。PG-931 TFA 是一种强效的黑素皮质素 4 (MC4) 受体(IC50=0.58 nM) 激动剂,比 hMC3R (IC50=55 nM) 或 hMC5R (IC50=2.4 nM)更具选择性。PG-931 TFA 在动物实验模型中,可逆转出血休克,防止体内多器官损伤。 |