3
1
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14365 |
AZ PFKFB3 26
|
Glucokinase | Metabolism |
AZ PFKFB3 26 是一种有效的特异性 PFKFB3 抑制剂,IC50 为 23 nM。 PFKFB1 和 PFKFB2 的 IC50 分别为 2.06 和 0.384 μM。 | |||
T62894 | AZ-PFKFB3-67 quarterhydrate | ||
AZ-PFKFB3-67 quarterhydrate 是一种选择性的、高效的代谢激酶 PFKFB3 激酶抑制剂,作用于 PFKFB3 (IC50: 11 nM)、PFKFB2 (IC50: 159 nM) 和 PFKFB1 (IC50: 1130 nM)。 | |||
T26730 | AZ-PFKFB3-67 | ||
AZ-PFKFB3-67 is a novel, potent and selective inhibitor of PFKFB3. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00868 |
PFKFB1 Protein, Human, Recombinant (His)
PFKFB1,F6PK,6-P2ase liver isozyme,6-bispho... |
Human | HEK293 Cells |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activit... |