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Cat. No. | Product Name | Target | Signaling Pathways |
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TP2466 |
Platelet factor 4 (59-70)
PF4 (59-70) |
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Platelet factor 4 (59-70) elicits human neutrophil & monocyte chemotaxis. | |||
T12437 |
PF429242 dihydrochloride
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S1P Receptor | GPCR/G Protein |
PF429242 dihydrochloride 是一种可逆的竞争性 SREBP 位点 1 蛋白酶抑制剂,IC50值为175 nM。 | |||
T75242 |
Bivalirudin TFA
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Bivalirudin TFA 是20个氨基多肽,可逆地抑制凝血酶。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04622 |
PF4V1 Protein, Human, Recombinant (mFc)
PF4A,CXCL4V1,platelet factor ... |
Human | HEK293 Cells |
PF4V1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 34.6 kDa and the accession number is P10720. | |||
TMPH-03121 |
CXCL4 Protein, Pig, Recombinant (His & Myc)
SCYB4,CXCL4,PF4,Platelet... |
Sus scrofa (Pig) | E. coli |
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation. CXCL4 Protein, Pig, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.1 kDa and the accession number is P30034. | |||
TMPJ-00012 |
CXCL4 Protein, Human, Recombinant (His)
SCYB4,PF4,Iroplact,Platelet Facto... |
Human | HEK293 Cells |
Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-binding sites at the C-terminal region and binds heparin with high affinity. The active CXCL4 protein is a tetramer. Human and mouse CXCL4 share 64% sequence identity. CXCL4 is chemotactic for neutrophils, fibroblasts and monocytes and plays a critical role in inflammation and wound repair. CXCL4 functions via a splice variant of the chemokin... | |||
TMPY-00218 |
CXCL7 Protein, Mouse, Recombinant (aa 40-113, His)
b-TG1,pro-platelet basic protein (chemokine (C-X-C motif) li... |
Mouse | E. coli |
CXCL7 Protein, Mouse, Recombinant (aa 40-113, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10.4 kDa and the accession number is Q9EQI5. | |||
TMPY-00469 |
CXCL7 Protein, Human, Recombinant (His)
LA-PF4,TC1,LDGF,NAP-2,TGB,CTAP-III,PBP,Bet... |
Human | E. coli |
CXCL7 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 9.9 kDa and the accession number is P02775. | |||
TMPY-00741 |
CXCL4 Protein, Human, Recombinant
PF-4,platelet factor 4,SCYB4<... |
Human | E. coli |
Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils a... | |||
TMPK-01248 |
CXCL4 Protein, Mouse, Recombinant (hFc)
PF-4,CXCL4,SCYB4,Oncosta... |
Mouse | HEK293 Cells |
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes. CXCL4 Protein, Mouse, Recombinant (hFc) is expressed in H... | |||
TMPK-00012 |
CXCL4 Protein, Human, Recombinant (His & Avi)
PF-4,CXCL4,SCYB4,Oncosta... |
Human | E. coli |
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes. CXCL4 Protein, Human, Recombinant (His & Avi) is expresse... | |||
TMPK-00014 |
CXCL4 Protein, Human, Recombinant (hFc)
Iroplact,CXCL4,Oncostatin-A,PF-4,... |
Human | HEK293 Cells |
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes. CXCL4 Protein, Human, Recombinant (hFc) is expressed in H... | |||
TMPK-00013 |
CXCL4 Protein, Human, Recombinant (His & Avi), Biotinylated
SCYB4,MGC138298,PF-4,Iroplact,Onc... |
Human | E. coli |
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes. CXCL4 Protein, Human, Recombinant (His & Avi), Biotinylat... | |||
TMPJ-00993 |
CCL5 Protein, Rat, Recombinant (E. coli, His)
Small-inducible cytokine A5,SIS-δ,C-C motif chemokine 5,T-ce... |
Rat | E. coli |
C-C motif chemokine 5(CCL5) is a β-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. CCL5 is secreted by many cell types at inflammatory sites, and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. Inflammatory responses can be impaired by the sequestration of CCL5 by the cytomegalovirus protein US28. Oligomerization of CCL5 on glycosaminoglycans is required for CCR1mediated leu... |