Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12419 |
PF-04634817 succinate
|
COX | Immunology/Inflammation; Neuroscience |
PF-0463481 succinate is a potent and orally active dual antagonist of CCR2/CCR5 with comparable human and rodent CCR2 potency with IC50 of 20.8 nM. | |||
T12419L | PF-04634817 | CCR | Immunology/Inflammation; Microbiology/Virology |
PF-0463481 is safe and well-tolerated and has the potential for the study of diabetic nephropathy. PF-0463481 is an effective and orally active dual CCR2/CCR5 antagonist. It also has comparable human and rodent CCR2 potency (rat IC50=20.8 nM). PF-0463481 |